Sökning: "matrix metalloproteinaser"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden matrix metalloproteinaser.

1. 1. Injury-induced activation of vascular smooth muscle cells. Role of specific gene expression and intracellular signalling pathways

   Författare :Cecilia Lövdahl; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metalloproteinase; extracellular matrix; ERK1 2 signalling; migration; proliferation; injury; vessel wall; smooth muscle cell; Medicine human and vertebrates ; Medicin människa och djur ;

   Sammanfattning : Migration and proliferation of smooth muscle cells (SMC) are important events in the development of atherosclerosis and restenosis following angioplastic surgery. It is important to gain further knowledge about the mechanisms regulating SMC form and function in order to understand the underlying disease process. LÄS MER

3. 2. Role of platelets and neutrophils in regulating trypsinogen activation and tissue damage in acute pancreatitis

   Författare :Aree Abdulla; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protease activation; adhesion molecule; chemokine; intravital flourecence microscopy; matrix metalloproteinase.;

   Sammanfattning : Acute pancreatitis is an inflammatory disease characterized by a diverse spectrum of clinical presentations ranging from a mild and self-limiting to a severe and systemic disorder. The relationship between inflammation and proteolytic activation in pancreatitis is an elusive issue. LÄS MER

4. 3. The collagen fibrillar network: Sequential degradation of its constituents by tissue metalloproteinases

   Författare :Terrence Heathfield; Enheten för led- och mjukvävnadsforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolism; Metabolism; Biochemistry; collagen; fibromodulin; cartilage; osteoarthritis; Biokemi;

   Sammanfattning : The cartilage matrix is made up of a fibrillar meshwork comprising type II collagen and other associated proteins. One main function of this network is to retain the large aggregating proteoglycan, aggrecan, a vital component in the regulation of fluid flux in cartilage. LÄS MER

5. 4. Dentine caries : acid tolerant microorganisms and aspects on collagen degradation

   Författare :Anders Hedenbjörk Lager; Malmö högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dental Caries; Collagen; Cariogenic Agents;

   Sammanfattning : Karies är en stor folksjukdom, trots att den både kan förebyggas och behandlas effektivt. Om man inte ingriper preventivt och låter det naturliga förloppet råda, kommer kariesangreppet till slut att bryta igenom emaljen och involvera även den underliggande dentinvävnaden. LÄS MER

7. 5. Signaling and Adhesive Mechanisms in Acute Pancreatitis

   Författare :Darbaz Awla; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; trypsinogen activation; Acute pancreatitis; leukocyte recruitment and adhesion;

   Sammanfattning : Acute pancreatitis (AP) is an inflammatory disease with variable severity ranging from mild interstitial edematous to severe necrotizing disease. The overall mortality rate of AP is 8-9%. Specific treatment of AP is lacking which is partly related to an incomplete understanding of the basic pathophysiology behind the disease. LÄS MER