Sökning: "leptin receptor"

Visar resultat 1 - 5 av 47 avhandlingar innehållade orden leptin receptor.

  1. 1. Regulation of Leptin by Sexual Maturation and Energy Status in Male Atlantic Salmon (Salmo salar L.) Parr

    Författare :Susanne Trombley; Monika Schmitz; Sylvie Dufour; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Leptin; leptin receptor; Atlantic salmon; Salmo salar; sexual maturation; puberty; energy balance; hepatocytes; sex steriods; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : Leptin is a peripheral adiposity signal and a key hormone in energy balance regulation in mammals, acting as a link between nutritional status and the endocrine reproductive axis. If this is also the role of leptin in fish is not fully understood. LÄS MER

  2. 2. Role of leptin in energy balance and sexual maturation in male Atlantic salmo (Salmo salar L.) parr

    Författare :Susanne Trombley; Monika Schmitz; Bertil Borg; Cecilia Berg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; leptin; leptin receptor; sexual maturation; restricted feeding; Atlantic salmon; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : .... LÄS MER

  3. 3. Leptin endocrinology and energy homeostasis in salmonids

    Författare :Marcus Johansson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Leptin; Leptin binding-protein; Energy homeostasis; Oncorhynchus mykiss; Salvelinus alpinus; Adiposity; Food intake; Fasting; Refeeding; Catabolism; Anorexia;

    Sammanfattning : In salmonids, the physiological role of leptin is not completely elucidated. Nonetheless, the anorexigenic effect of leptin indicates a role in their energy homeostasis. This thesis focuses on advancing the understanding of the involvement of the leptin system in the regulation of energy homeo-stasis and food intake in teleost fish. LÄS MER

  4. 4. Genes implicated in the development of obesity and obesity-related disease

    Författare :Kajsa Lindell; Göteborgs universitet; []
    Nyckelord :obesity; adipose tissue; hypothalamus; leptin; leptin receptor; 5 untranslated region; hypertension; angiotensinogen; DNA microarray;

    Sammanfattning : Obesity is a major health problem because of its dramatic increase in prevalence and the association of obesity with type 2 diabetes, coronary heart disease, hypertension and stroke. Although mutations in certain genes have been shown to cause obesity, the molecular mechanisms underlying obesity and obesity-related disease are still largely unknown. LÄS MER

  5. 5. Prolactin receptor expression and prolactin-mediated effects in adipose tissue

    Författare :Charlotte Ling; Göteborgs universitet; []
    Nyckelord :adipose tissue; prolactin receptor; SOCS; leptin; resistin; lipoprotein lipase;

    Sammanfattning : The aim of this study was to investigate the presence of functional prolactin receptors (PRLRs) in white adipose tissue of mice and humans, and the possible functions mediated via PRLRs. In mouse white adipose tissue, three PRLR mRNA isoforms, L-, S2-, and S3-PRLR, and L-PRLR protein expression were detected. LÄS MER