Sökning: "human physiology"

Visar resultat 16 - 20 av 262 avhandlingar innehållade orden human physiology.

1. 16. Diabetes-induced Alterations in Renal Microcirculation and Metabolism

   Författare :Fredrik Palm; Per Liss; Peter Hansell; Per-Ola Carlsson; Gerald DiBona; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; diabetes mellitus; kidney; nephropathy; oxygen tension; haemodynamic; nitric oxide; oxygen consumption; radical oxygen species; polyol pathway; Fysiologi; Physiology; Fysiologi;

   Sammanfattning : Diabetes-induced renal complications, i.e. diabetes nephropathy, are a major cause of morbidity and mortality. The exact mechanism mediating the negative influence of hyperglycaemia on renal function is unclear, although several hypotheses have been postulated. LÄS MER

3. 17. The role of the alpha 7 nicotinic acetylcholine receptor in inflammation and brain injury

   Författare :Maria Hammarlund; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha 7 nicotinic acetylcholine receptor; inflammation; brain injury; CHRNA7; CHRFAM7A; stroke; hypoxia ischemia; neonatal encephalopathy; human; PBMC;

   Sammanfattning : The alpha 7 nicotinic acetylcholine receptors (α7nAChR) are expressed in the nervous system as well as on peripheral immune cells where it participates in the cholinergic anti-inflammatory pathway. Inflammation is a common component in the pathology of many diseases and injuries, including brain damage. LÄS MER

4. 18. Energy flow and metabolic efficiency attributed to brown adipose tissue

   Författare :Gabriella von Essen; Jan Nedergaard; Susanne Klaus; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brown adipose tissue; BAT; UCP1; diet-induced thermogenesis; DIT; obesity; high-fat diet; energy expenditure; fysiologi; Physiology;

   Sammanfattning : The large capacity of brown adipose tissue (BAT) to expend energy as heat makes it an interesting potential player in weight regulation and other metabolic conditions. This is of particular interest as it has been recognized that adult humans possess BAT. LÄS MER

5. 19. Ion channels and electrical activity in vascular smooth muscle: Effects of calcium store depletion, cholesterol and cholesterol-lowering drugs

   Författare :Andreas Bergdahl; Kärlfysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; statins; endothelin; cholesterol; caveolae; smooth muscle; TRP; Ca2 channels; SOC;

   Sammanfattning : Smooth muscle cells (SMCs) in the vessel wall contract to regulate blood flow and pressure, a function essential for normal circulation through tissues. On the other hand, migration and proliferation of SMCs are important factors in vascular disease, such as atherosclerosis and restenosis following surgical dilatation. LÄS MER

7. 20. Role of Melatonin, Neuropeptide S and Short Chain Fatty Acids in Regulation of Duodenal Mucosal Barrier Function and Motility

   Författare :Wan Salman Wan Saudi; Markus Sjöblom; Olof Nylander; Mark Berner-Hansen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 51Cr-EDTA; rat; in vivo; duodenum; enteric nervous system; paralytic ileus; parecoxib; bicarbonate secretion; motility; ethanol; HCl; melatonin; neuropeptide S; short chain fatty acids; chemosensing; Physiology; Fysiologi;

   Sammanfattning : The duodenal epithelium is regularly exposed to HCl, digestive enzymes, bacteria and toxins, and sometimes also to ethanol and drugs. The imbalance of aggressive factors in the intestinal lumen and mucosal barrier function increases the risk of tissue injury and inflammation. LÄS MER