Sökning: "enterochromaffin cell"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden enterochromaffin cell.

  1. 1. Novel Circulating and Tissue Biomarkers for Small Intestine Neuroendocrine Tumors and Lung Carcinoids

    Författare :Tao Cui; Valeria Giandomenico; Kjell Öberg; Apostolos V. Tsolakis; Marco Volante; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small intestine neuroendocrine tumors; lung carcinoids; Ma2 autoantibodies; immunohistochemistry; olfactory receptor 51E1; blood samples; antibody suspension bead array; 小肠神经内分泌肿瘤，肺类癌，Ma2自身抗体，免疫组化，嗅觉受体蛋白51E1， 血液样本，抗体悬浮磁珠阵列; Endokrinologi och Diabetologi; Endocrinology and Diabetology; Lung Medicine; Lungmedicin; Molecular Biology; Molekylärbiologi; Oncology; Onkologi;

    Sammanfattning : Small intestine neuroendocrine tumors (SI-NETs) and lung carcinoids (LCs) are relatively indolent tumors, which originate from neuroendocrine (NE) cells of the diffuse NE system. Metastases can spread before diagnosis. Thus, potential cures become unavailable, which entitles new biomarker development. LÄS MER

  3. 2. Rotavirus Disease Mechanisms Diarrhea, Vomiting and Inflammation : How and Why

    Författare :Marie Hagbom; Lennart Svensson; Karl-Eric Mangusson; Ove Lundgren; Niklas Arnberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Rotavirus infections cause diarrhea and vomiting that can lead to severe dehydration. Despite extensive tissue damage and cell death, the inflammatory response is very limited. LÄS MER

  4. 3. Small Intestinal Neuroendocrine Tumor Analyses : Somatostatin Analog Effects and MicroRNA Profiling

    Författare :Su-Chen Li; Valeria Giandomenico; Kjell Öberg; Marco Volante; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Small intestinal neuroendocrine tumors; Somatostatin analogs; Laser-capture microdissection; Microarray profiling and microRNA profiling; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : Small intestinal neuroendocrine tumors (SI-NETs) originate from serotonin-producing enterochromaffin (EC) cells in the intestinal mucosa. Somatostatin analogs (SSAs) are mainly used to control hormonal secretion and tumor growth. However, the molecular mechanisms leading to the control of SI-NETs are unknown. LÄS MER

  5. 4. Effects of Orexins, Guanylins and Feeding on Duodenal Bicarbonate Secretion and Enterocyte Intracellular Signaling

    Författare :Magnus Wilhelm Bengtsson; Gunnar Flemström; Olof Nylander; Karl E. O. Åkerman; Per M. Hellström; Uppsala universitet; []
    Nyckelord :Physiology; alkaline secretion; carbohydrates; central nervous system; cholinergic stimulation; duodenum; enteric nervous system; enterochromaffin cell; fasting; feeding; glucose; guanylyl cyclase C; humans; hypocretin; intra-arterial; in situ; intracerebroventricular; luminal acid; luzindole; orexin-B; SB-334867; Fysiologi;

    Sammanfattning : The duodenal epithelium secretes bicarbonate ions and this is regarded as the primary defence mechanism against the acid discharged from the stomach. For an efficient protection, the duodenum must also function as a sensory organ identifying luminal factors. LÄS MER

  7. 5. The Duodenal Mucosal Bicarbonate Secretion : Role of Melatonin in Neurohumoral Control and Cellular Signaling

    Författare :Markus Sjöblom; Gunnar Flemström; Olof Nylander; Karl EO Åkerman; Per M. Hellström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; alkaline secretion; central nervous system; duodenal enterocyte; duodenal ulcer; duodenum; enterochromaffin cell; human; intraarterial; intracellular calcium; intracerebroventricular; melatonin; rat; vagal nerve; Fysiologi; Physiology; Fysiologi;

    Sammanfattning : The duodenal lumen is exposed to aggressive factors with a high potential to cause damage to the mucosa. Bicarbonate secretion by the duodenal mucosa is accepted as the primary important defense mechanism against the hydrochloric acid intermittently expelled from the stomach. LÄS MER