Sökning: "Small intestinal neuroendocrine tumors"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Small intestinal neuroendocrine tumors.

1. 1. Small Intestinal Neuroendocrine Tumors : Clinical Studies, Novel Serum Biomarkers and Sensitivity to Cytotoxic and Targeted Agents

   Författare :Kosmas Daskalakis; Peter Stålberg; Per Hellman; Olov Norlén; Robert Bränström; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SI-NET; fibrosis; locoregional surgery; liver transplantation; biomarkers; ex vivo sensitivity.;

   Sammanfattning : Small Intestinal Neuroendocrine Tumors (SI-NETs) are indolent neoplasms with an increasing annual incidence of approximately 1/100 000 people. They are often diagnosed at a late stage, restricting treatment efficacy. LÄS MER

3. 2. Small Intestinal Neuroendocrine Tumor : A Rare Malignancy with Favorable Outcome

   Författare :Olov Norlén; Peter Stålberg; Per Hellman; Peyman Björklund; Anders Sundin; Peter Naredi; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroendocrine tumor; peritoneal carcinomatosis; single nucleotide polymorphism array; liver metastases; radiofrequency ablation; liver surgery; positron emission tomography; somatostatin analogs; cholecystectomy; Kirurgi; Surgery;

   Sammanfattning : Small intestinal neuroendocrine tumor (SI-NET) is the most common small bowel tumor in Europe and USA, with an annual incidence of around 0.3-1.3/100000 persons. LÄS MER

4. 3. Small Intestinal Neuroendocrine Tumor Analyses : Somatostatin Analog Effects and MicroRNA Profiling

   Författare :Su-Chen Li; Valeria Giandomenico; Kjell Öberg; Marco Volante; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Small intestinal neuroendocrine tumors; Somatostatin analogs; Laser-capture microdissection; Microarray profiling and microRNA profiling; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

   Sammanfattning : Small intestinal neuroendocrine tumors (SI-NETs) originate from serotonin-producing enterochromaffin (EC) cells in the intestinal mucosa. Somatostatin analogs (SSAs) are mainly used to control hormonal secretion and tumor growth. However, the molecular mechanisms leading to the control of SI-NETs are unknown. LÄS MER

5. 4. Theranostics in Neuroendocrine Tumors : Somatostatin Receptor Imaging and Therapy

   Författare :Ezgi Ilan; Mark Lubberink; Peter Bernhardt; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 177Lu-DOTATATE; 68Ga-DOTATATE; 68Ga-DOTATOC; PRRT; Theranostics; PET CT; SPECT CT; Neuroendocrine tumors; Somatostatin receptors; Medicinsk radiofysik; Medical Radiophysics;

   Sammanfattning : Neuroendocrine tumors (NETs) are characterized by cellular overexpression of somatostatin receptors (SSTR), which allows for the use of radiolabeled somatostatin analogs (SSA) for both imaging and therapy. Because NETs often are diagnosed at a metastatic stage, curative surgery is not possible. LÄS MER

7. 5. Peptide Receptor Radionuclide Therapy in Neuroendocrine Neoplasms : Aspects of tumour characteristics, receptor recycling and peptide mass

   Författare :Ulrika Jahn; Anders Sundin; Mark Lubberink; Ulrike Garske-Román; Mona-Elisabeth Rootwelt-Revheim; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroendocrine tumors; Peptide receptor radionuclide therapy PRRT ; Peptide; Small-Intestinal; Pancreatic; Dosimetry; Somatostatin receptor;

   Sammanfattning : Neuroendocrine neoplasm (NEN) can arise in any part of the body, but most commonly in the lungs, bronchi, and the gastrointestinal tract including the pancreas. They combine neuroendocrine and tissue-of-origin-specific characteristics; explaining different symptoms depending on the organ of origin. LÄS MER