Sökning: "diol"
Visar resultat 11 - 15 av 72 avhandlingar innehållade ordet diol.
11. Cancer Risk Assessment of Glycidol : Evaluation of a Multiplicative Risk Model for Genotoxic Compounds
Sammanfattning : Humans are exposed to chemical compounds in everyday life, both from the environment and from endogenous processes. Some compounds constitute a risk for cancer development. One such compound is glycidol, which is genotoxic and an animal carcinogen. It is the model compound of this work, partly due to its presence in food. LÄS MER
12. Amino acids with relevance to health, climate and the environment : Development of mass spectrometric methods
Sammanfattning : Amino acids play vital roles in health, either in their native form or chemically modified. Some studies have linked certain non-proteinogenic amino acids to neurodegenerative diseases, such as in the case of β-methylaminoalanine (BMAA). LÄS MER
13. Nuclear receptor functions in the central nervous system : clues from knockout mice
Sammanfattning : The nuclear receptor (NR) superfamily is the largest known family of transcription factors in eukaryotes. In the 1980 s when the size of the NR family and the scope of the functions of its members were being discovered, tissue distribution studies revealed that the mRNAs of many of these receptors were expressed in the central nervous system. LÄS MER
14. Factors Influencing the Yield of Mutations Induced by Polycyclic Aromatic Hydrocarbons in Mammalian Cells
Sammanfattning : Environmental contaminants are ubiquitously present in the urban environment, this has the implication that humans are exposed to toxic and carcinogenic chemicals. Polycyclic aromatic hydrocarbons (PAH) are one type of environmental contaminants, which are produced by combustion of organic compounds. LÄS MER
15. Insights into dynamic covalent chemistry for bioconjugation applications
Sammanfattning : Dynamic covalent chemistry (DCC) is currently exploited in several areas of biomedical applications such as in drug discovery, sensing, molecular separation, catalysis etc. Hydrazone and oxime chemistry have several advantages, such as mild reaction conditions, selectivity, efficiency, and biocompatibility and therefore, have the potential to be for bioconjugation applications. LÄS MER
