Sökning: "delayed entry"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden delayed entry.

  1. 1. Regulation of CDK dephosphorylation in mitotic entry

    Författare :Arne Lindqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cell cycle progression is orchestrated by the activity of a Cyclin dependent kinase (Cdk) in complex with a Cyclin. The key regulator of early mitotic events is the Cyclin B1/Cdk1 complex. In G2, Cyclin B1/Cdk1 is kept inactive by phosphorylation in the active site of Cdk1. LÄS MER

  3. 2. Regional Economics, Trade, and Transport Infrastructure

    Författare :Nicholas Sheard; Rikard Forslid; Keith Head; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Regional policy; agglomeration; firm heterogeneity; export market entry; export timing; air travel; infrastructure; Economics; nationalekonomi;

    Sammanfattning : “Regional Policy in a Multiregional Setting: When the Poorest are Hurt by Subsidies” Regional subsidies have a positive short-term effect on the recipient regions, but as they alter migration patterns the long-term effects are less clear. This paper demonstrates using a three-region general equilibrium model that subsidising the poorest region may be to its detriment in the long term and thereby increase inter-regional inequality, if the subsidy draws firms from a nearby region that would function better as a production centre. LÄS MER

  4. 3. Studies of anemia in the myelodysplastic syndromes

    Författare :Martin Jädersten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Myelodysplasia; growth factors; Cox regression; delayed entry; left truncation; mortality; international prognostic scoring system; IPSS; who-classification based prognostic scoring system; WPSS; thalidomide analogue; IMiD; hematopoietic stem cell; adhesion; stroma; matrix; osteonectin; matricellular protein; NPM1; immunohistochemistry.;

    Sammanfattning : Background: The myelodysplastic syndromes (MDS) constitute a heterogeneous group of malignant bone marrow disorders, characterized by chronic anemia and increased risk of transformation to acute myeloid leukemia (AML). The first line therapy of anemia in MDS is erythropoietin (EPO) with or without granulocyte colony-stimulating factor (G-CSF). LÄS MER

  5. 4. HAMLET - In vivo effects and mechanisms of tumor-cell death

    Författare :Lotta Gustafsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Biomedical sciences; proteasome stress; HAMLET; human milk; tumor-cell death; clinical trial; rat xenograft model; skin papilloma; glioblastoma;

    Sammanfattning : HAMLET (human alpha-lactalbumin made lethal to tumor cells), a molecular complex derived from human milk, is an interesting new tool in cancer research since it induces programmed cell death in tumor cells while leaving normal, differentiated cells unharmed. The in vivo effects of HAMLET were studied in a rat xenograft model of human glioblastoma. LÄS MER

  7. 5. Konkurrens, samarbete och koncentration. Kalkstens- och cementindustrin i Sverige 1871-1982

    Författare :Malin Dahlström; Göteborgs universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Ekonomisk historia; Cartels; cooperation; monopoly; concentration; competition; cement; limestone; industry; cartel legislation;

    Sammanfattning : This dissertation examines cartels and cooperation. The literature about cartels and cooperation is in many ways contradictory; many of the studies that have been made come to different results. Several of the implications from former research are valid only within their context. LÄS MER