Sökning: "osteonectin"

Hittade 3 avhandlingar innehållade ordet osteonectin.

  1. 1. Gene expression during hard tissue formation

    Författare :Catharina Ellerström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :bone; dentin; mRNA; fibrillar collagens; osteonectin; fibronectin; development; rat;

    Sammanfattning : The purpose of this thesis was to study the formation of the extracellular matrix (ECM) of bone and dentin during development. Molecular techniques, such as in situ hybridization and RT-PCR, were used to investigate the occurrence of specific gene products in formative cells. LÄS MER

  3. 2. Studies of anemia in the myelodysplastic syndromes

    Författare :Martin Jädersten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Myelodysplasia; growth factors; Cox regression; delayed entry; left truncation; mortality; international prognostic scoring system; IPSS; who-classification based prognostic scoring system; WPSS; thalidomide analogue; IMiD; hematopoietic stem cell; adhesion; stroma; matrix; osteonectin; matricellular protein; NPM1; immunohistochemistry.;

    Sammanfattning : Background: The myelodysplastic syndromes (MDS) constitute a heterogeneous group of malignant bone marrow disorders, characterized by chronic anemia and increased risk of transformation to acute myeloid leukemia (AML). The first line therapy of anemia in MDS is erythropoietin (EPO) with or without granulocyte colony-stimulating factor (G-CSF). LÄS MER

  4. 3. Tissue responses to bone-implant biomaterials

    Författare :Haihong Liao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Gene expression; interface; mineralization; nacre; osteoblast; osteoclast; titanium;

    Sammanfattning : The purpose of the studies was to understand the mechanisms which underlie the interaction between tissue and bone-implant biomaterials. Tissue and naturally occurring aragonite nacre interaction was systematically studied for the first time by combined histological examination, cellular and molecular biological approaches. LÄS MER