Sökning: "defense mechanisms"

Visar resultat 6 - 10 av 397 avhandlingar innehållade orden defense mechanisms.

  1. 6. Biophysical investigations of ribonucleotide reductase : Activation and inhibition mechanisms

    Författare :Maria Öhrström; Astrid Gräslund; Anders Hofer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; Molekylär biofysik; Biophysics; biofysik;

    Sammanfattning : Ribonucleotide reductase (RNR) is the enzyme responsible for de novo synthesis of deoxyribonucleotides, needed for both synthesis and repair of cellular DNA. The RNRs known so far are divided into three distinct classes; I, II and III. The conventional class I enzyme is composed of two separate subunits. LÄS MER

  3. 7. Cell-penetrating peptides for oligonucleotide delivery : Design and uptake mechanisms

    Författare :Staffan Lindberg; Ülo Langel; Arwyn Jones; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; gene therapy; scavenger receptors; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : The use of oligonucleotides for gene therapy has the potential to efficiently treat a plethora of diseases with minimal side effects. However, the use of oligonucleotides is hampered by the properties of these molecules, which make it essentially impossible for them to permeate the cellular membrane. LÄS MER

  4. 8. Cellular Responses to Arsenite and Cadmium - Mechanisms of Toxicity and Defense in Saccharomyces cerevisiae

    Författare :Therese Jacobson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; arsenic; arsenite; cadmium; glutathione; extracellular defense; protein aggregation; chaperones; proteasome; Saccharomyces cerevisiae;

    Sammanfattning : All biological systems have to cope with a wide range of metals that are present in the environment. Metals can be essential or beneficial for life, inert or non-essential and toxic, often depending on their chemical form and concentration. Most organisms have evolved defense mechanisms in order to deal with toxic metals. LÄS MER

  5. 9. Plant pathogen defense: Signalling, resistance and cell death

    Författare :Oskar N. Johansson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Pseudomonas; cell death; pathogens; plant defense; hypersensitive response; glycolipid; reactive oxygen species; blumeria graminis; erysiphe pisi;

    Sammanfattning : Pathogenic microorganisms are present everywhere in nature and infect both animals and plants. Phytopathogenic microorganisms cause diseases on plants, and are responsible for crop loss amounting in the order billions of dollars annually. LÄS MER

  7. 10. Regulatory mechanisms of amino acid-induced signaling in Saccharomyces cerevisiae

    Författare :Deike J. Omnus; Per O. Ljungdahl; Claudio De Virgilio; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Signal transduction; regulatory mechanisms; nutrient sensing; Saccharomyces cerevisiae; Cell Biology; cellbiologi;

    Sammanfattning : This thesis describes studies aimed at elucidating the molecular mechanisms that regulate the SPS (Ssy1-Ptr3-Ssy5) signal transduction pathway in the yeast Saccharomyces cerevisiae. This pathway is induced by extracellular amino acids and facilitates their uptake. LÄS MER