Sökning: "hypersensitive response"
Visar resultat 1 - 5 av 24 avhandlingar innehållade orden hypersensitive response.
1. DNA Damage Response of Normal Epidermis in the Clinical Setting of Fractionated Radiotherapy : Evidence of a preserved low-dose hypersensitivity response
Sammanfattning : Investigations of DNA damage response (DDR) mechanisms in normal tissues have implications for both cancer prevention and treatments. The accumulating knowledge about protein function and molecular markers makes it possible to directly trace and interpret cellular DDR in a tissue context. LÄS MER
2. Plant pathogen defense: Signalling, resistance and cell death
Sammanfattning : Pathogenic microorganisms are present everywhere in nature and infect both animals and plants. Phytopathogenic microorganisms cause diseases on plants, and are responsible for crop loss amounting in the order billions of dollars annually. LÄS MER
3. Defence and signalling in Potato-Phytophthora infestans interactions
Sammanfattning : Potato is one of the major food crops and its yield is severely affected by late blight disease caused by Phytophthora infestans. P. infestans has the ability to manipulate plant defence signalling by secreting effector molecules causing so called effector triggered susceptibility. LÄS MER
4. Clinical and experimental studies in corticosteroid contact allergy
Sammanfattning : Corticosteroids are anti-inflammatory and anti-proliferative substances that also can induce sensitization, mainly through skin contact. In a sensitized individual, it can be hard to disclose the contact allergy at patch testing because the anti-inflammatory effect may mask the allergic contact reaction. LÄS MER
5. Emerging roles of PFKFB3 and CX3CR1 in the DNA damage response and their potential as therapeutic targets in cancer
Sammanfattning : Genomic instability in cancer is exploited therapeutically using DNA damaging therapies that cause irreparable lesions above the threshold of tolerable DNA damage levels. Nevertheless, toxic side effects on healthy tissues limit the therapeutic potential of such therapies. LÄS MER