Sökning: "conserved"

Visar resultat 1 - 5 av 985 avhandlingar innehållade ordet conserved.

  1. 1. Influenza Neuraminidase : Conserved features of a rapidly mutating virus

    Författare :Henrik Östbye; Pia Ädelroth; Anice Lowen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; influenza; virology; neuraminidase; biokemi; Biochemistry;

    Sammanfattning : Influenza A viruses (IAVs) of the H1N1 and H3N2 serotypes are the major cause of seasonal influenza epidemics. IAVs are labeled based on the antigenic properties of the two surface glycoproteins and main antigens: hemagglutinin (HA/H) and neuraminidase (NA/N). LÄS MER

  3. 2. Conserved structure-function relationships in the mediator complex

    Författare :Tomas Linder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Transcription; Mediator; yeast;

    Sammanfattning : The Mediator complex is an essential multiprotein coregulator of RNA polymerase II (pol II)- dependent transcription in fungi and metazoans. Mediator interacts directly with both pol II and sequence-specific transcriptional regulators and thus acting as a bridge between the two. LÄS MER

  4. 3. Characterisation of the conserved Helicobacter pyloriproteins AhpC and HpaA

    Författare :Anneli Maria Lundström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Background: Infection with Helicobacter pylori gives rise to gastritis and may cause duodenal and gastric ulcers and gastric carcinoma in humans. The infection may induce an immune response against different antigens, among them a 26 kDa protein (AhpC) and a 29 kDa protein (HpaA). Aims: The aims were to characterise the 26 kDa and 29 kDa H. LÄS MER

  5. 4. Retroviral long Terminal Repeats; Structure, Detection and Phylogeny

    Författare :Farid Benachenhou; Jonas Blomberg; Göran Sperber; Aris Katzourakis; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Retrovirus; long terminal repeats; hidden Markov models; phylogeny; alignment; conserved motif; stem-loop; Clinical virology; Klinisk virologi; Klinisk virologi; Clinical Virology;

    Sammanfattning : Long terminal repeats (LTRs) are non-coding repeats flanking the protein-coding genes of LTR retrotransposons. The variability of LTRs poses a challenge in studying them. Hidden Markov models (HMMs), probabilistic models widely used in pattern recognition, are useful in dealing with this variability. LÄS MER

  7. 5. Evolutionary Analysis of the Insulin-Relaxin Gene Family from the Perspective of Gene and Genome Duplication Events

    Författare :Robert Piotr Olinski; Finn Hallböök; Mike Thorndyke; Pierre Pontarotti; Uppsala universitet; []
    Nyckelord :Neurosciences; insulin; relaxin; insulin-like protein; gene duplication; paralogous region; Ciona intestinalis; conserved synteny; ortholog; Drosophila melanogaster; Neurovetenskap;

    Sammanfattning : Paralogs arise by duplications and belong to families. Ten paralogs (insulin; IGF-1 and -2; INSL3-6 and 3-relaxins) constitute the human insulin-relaxin family. The aim of this study was to outline the duplications that gave rise to the vertebrate insulin-relaxin genes and the chromosomal regions in which they reside. LÄS MER