Sökning: "congenital malformation"
Visar resultat 1 - 5 av 38 avhandlingar innehållade orden congenital malformation.
1. Maternal smoking and congenital malformations
Sammanfattning : About two percent of Swedish newborn infants are born with a significant congenital malformations which is reported to the Swedish Registry of Congenital Malformations (RCM), and/or the Swedish Medical Birth Registry (MBR). In spite of persistent public health recommendations, about 16% of the Swedish pregnant women are smoking during pregnancy (1996). LÄS MER
2. Role of embryonic mitochondria in the generation of congenital malformations in diabetic pregnancy
Sammanfattning : Diabetic pregnancy is associated with an increased incidence of congenital malformations. The teratologicalmechanism may be related to an alteration of embryonic organogenesis by maternal metabolic derangementsduring early gestation. LÄS MER
3. 12-14 week scan with emphasis on risk assessment for fetal structural malformations and fetal loss
Sammanfattning : The aim was to evaluate first trimester nuchal translucency (NT) measurement for detection and risk assessment of fetal malformations and fetal loss. 39 572 pregnant women were randomised to either a routine ultrasound scan at 12-14 weeks including NT measurement or to a routine scan at 18-20 weeks. LÄS MER
4. Developmental disturbances of the embryo in diabetic pregnancy
Sammanfattning : Maternal diabetes during pregnancy constitutes an increased risk for congenital malformation in the offspring. Previous studies have suggested that diabetic embryopathy is associated with an excess of reactive oxygen species (ROS) as well as with a disturbance of prostaglandin (PG) metabolism. LÄS MER
5. Molecular Characterisation of Structural Chromosomal Abnormalities Associated with Congenital Disorders
Sammanfattning : Chromosomal abnormalities are defined as changes in the chromosome structure and fall in one of two categories. The first category is numerical alterations while the second category consists of structural abnormalities. Structural chromosomal abnormalities do not always interrupt genes in order to cause disease. LÄS MER