Sökning: "White adipose tissue"

Visar resultat 1 - 5 av 64 avhandlingar innehållade orden White adipose tissue.

1. 1. Brown is the new white: consequences of white adipose tissue alterations in Huntington's disease

   Författare :Andy Mccourt; Biomarkörer vid hjärnsjukdomar; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington’s disease; weight loss; white adipose tissue; brown adipose tissue; peripheral symptoms; R6 2 mice; UCP1; CREB1; gene expression;

   Sammanfattning : Huntington's disease (HD) is a devastating, inherited neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. Peripheral symptoms, such as skeletal muscle wasting, progressive weight loss, altered body composition and endocrine disturbances exist alongside neurodegeneration. LÄS MER

3. 2. Who is Who in the Adipose Organ : A look at the Heterogeneity of Adipocyte Biology

   Författare :Jasper de Jong; Jan Nedergaard; Christian Wolfrum; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipose tissue; Adipocyte; Brown; White; Brite Beige; Physiology; fysiologi; Physiology;

   Sammanfattning : The increasing prevalence of obesity and related health complications, such as type 2 diabetes, cardiovascular disease and cancer, demands thorough investigation of the underlying processes. One of the key tissues investigated in this context is adipose tissue. LÄS MER

4. 3. Prolactin receptor expression and prolactin-mediated effects in adipose tissue

   Författare :Charlotte Ling; Göteborgs universitet; []
   Nyckelord :adipose tissue; prolactin receptor; SOCS; leptin; resistin; lipoprotein lipase;

   Sammanfattning : The aim of this study was to investigate the presence of functional prolactin receptors (PRLRs) in white adipose tissue of mice and humans, and the possible functions mediated via PRLRs. In mouse white adipose tissue, three PRLR mRNA isoforms, L-, S2-, and S3-PRLR, and L-PRLR protein expression were detected. LÄS MER

5. 4. Adipose Tissue Heterogeneity - Development and Application of Nonlinear Microscopy Methods

   Författare :Alexandra Paul; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; least squares decomposition; stem cells; multivariate spectral analysis; obesity; adipose tissue; adipogenesis; broadband coherent anti-Stokes Raman scattering; extracellular matrix;

   Sammanfattning : Although the negative health impacts of obesity have been well documented, the number of overweight or obese patients has and is predicted to continue rising. One of the causal factors of obesity is a constant positive energy balance mainly from excessively high caloric intake from food compared with limited physical activity (caloric expenditure). LÄS MER

7. 5. Magnetic Resonance Imaging of Human Brown Adipose Tissue : Methodological Development and Application

   Författare :Elin Lundström; Joel Kullberg; Håkan Ahlström; Lars Johansson; Robin Strand; Sven Månsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brown adipose tissue; Magnetic resonance imaging; Positron emission tomography; Image segmentation; Glucose metabolism;

   Sammanfattning : Brown adipose tissue (BAT) is a thermogenic organ with the main human depot located in the cervical-supraclavicular (sBAT) region. BAT is proposed as a potential therapeutic target for obesity and diabetes. LÄS MER