Sökning: "Tyrosine"

Visar resultat 21 - 25 av 671 avhandlingar innehållade ordet Tyrosine.

  1. 21. The FLT3 Tyrosine Kinase in Leukemia : Deciphering the Downstream Signaling Events and Drug-Escape Mechanisms

    Författare :Amanda Nordigården; Jan-Ingvar Jönsson; Mickael Sigvardsson; Alexander Vener; Bengt Hallberg; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Acute myeloid leukemia (AML) is a severe disease, which originates in blood-forming cells. Although major advances in understanding the biology of AML, the majority of patients eventually succumb to the disease. LÄS MER

  3. 22. Structure and function of the SH3 domain from Bruton´s tyrosine kinase

    Författare :Henrik Hansson; KTH; []
    Nyckelord :nuclear magnetic resonance; src homology 3; bruton s tyrosine kinase; x-linked agammaglobulinemia; gel permeation chromatography; signal transduction;

    Sammanfattning : .... LÄS MER

  4. 23. FLT3 and KIT in acute myeloid leukemia. Translational studies on oncogenic signaling from receptor tyrosine kinases. : Translational studies on oncogenic signaling from receptor tyrosine kinases

    Författare :OSCAR LINDBLAD; Avdelningen för translationell cancerforskning; []
    Nyckelord :Acute myeloid leukemia; FLT3-ITD; KIT; tyrosine kinase receptors;

    Sammanfattning : .... LÄS MER

  5. 24. Aspects on long-term treatment with tyrosine kinase inhibitors in Chronic myeloid leukemia

    Författare :Sofia Jönsson; Göteborgs universitet; []
    Nyckelord :Chronic myeloid leukemia; tyrosine kinase inhibitor; imatinib; molecular response; adherence; mesechymal stem cells; osteoblast differentiation; dasatinib;

    Sammanfattning : Chronic myeloid leukemia (CML) is caused by the tyrosine kinase activity of the oncoprotein BCR-ABL. The introduction of tyrosine kinase inhibitors (TKIs) targeting BCR-ABL has profoundly changed the prognosis of CML. Currently, there are three TKIs approved for treatment of CML, imatinib, nilotinib and dasatinib. LÄS MER

  7. 25. Protein tyrosine kinases and the regulation of signalling and adhesion in drosophila melanogaster

    Författare :Caroline Grabbe; Ruth Palmer; Tapio Heino; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Signalling; Adhesion; Protein Tyrosine Kinase; Development; Endocytosis; Molecular biology; Molekylärbiologi;

    Sammanfattning : In order to build a multi-cellular organism and to regulate cellular functions, cells need to communicate with each other, as well as tightly regulate their behaviour in response to environmental changes. For these purposes all eukaryotic cells express a large number of membrane spanning receptors that either themselves contain catalytic activity or via cytoplasmic effector enzymes, function to transmit “signals” from the cell exterior to induce appropriate responses within the cell. LÄS MER