Sökning: "Endocytosis"

Visar resultat 1 - 5 av 128 avhandlingar innehållade ordet Endocytosis.

  1. 1. Ubiquitination and Receptor Endocytosis

    Författare :Kaisa Haglund; Carl-Henrik Heldin; Ivan Dikic; Harald Stenmark; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Ubiquitination; receptor tyrosine kinase; endocytosis; Cbl; CIN85; EGFR; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : Protein ubiquitination is an evolutionary conserved mechanism that controls a wide variety of cellular functions. Polyubiquitinated proteins are generally degraded in the proteasome, whereas monoubiquitination controls various other cellular processes, including endocytosis and endosomal sorting. LÄS MER

  3. 2. Endocytosis by human dendritic cells

    Författare :Linda Andersson; Malmö högskola; []
    Nyckelord :human dendritic cells; endocytosis;

    Sammanfattning : Dendritic cells (DCs) are specialized antigen-presenting cells with the ability to internalize antigen, and present antigen-derived peptides to T cells. The functions of DCs depend on the subset, as well as their location and activation state. LÄS MER

  4. 3. Sorting nexin 9 in clathrin-mediated endocytosis

    Författare :Richard Lundmark; Sven Carlsson; Elizabeth Smythe; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; sorting nexin; dynamin; clathrin; endocytosis; human; adaptor protein complexes; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Clathrin-mediated endocytosis is a process by which cells can internalise diverse molecules such as nutrients, antigens and signalling-surface receptors. The creation of clathrin-coated vesicles demands interplay between the plasma membrane lipids, cargo molecules and the proteins that build up the coat. LÄS MER

  5. 4. Cbl in Regulation of Growth Factor Receptor Endocytosis and Actin Dynamics

    Författare :Iwona Szymkiewicz; Ivan Dikic; Silvia Giordano; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; RTK; Cbl; endocytosis; ubiquitination; actin; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Proteins belonging to the Cbl family are multidomain scaffolds that participate in numerous processes, assembling signaling complexes and mediating attachment of ubiquitin to receptor and non-receptor tyrosine kinases.We characterized a novel role for Cbl and Cbl-b in ligand-dependent internalization of growth factor receptors. LÄS MER

  7. 5. Dissecting sterol function during clathrin-dependent endocytosis and cytokinesis in Arabidopsis thaliana

    Författare :Márcia Frescatada-Rosa; Markus Grebe; Wolfgang Lukowitz; Umeå universitet; []
    Nyckelord :Arabidopsis; membrane; sterols; cytokinesis; KNOLLE; endocytosis; clathrin; DRP1A; Developmental Biology; miljömedicinsk utvecklingsbiologi; molekylärbiologi; Molecular Biology; molecular cell biology; molekylär cellbiologi;

    Sammanfattning : Sterols are lipid components of eukaryotic membranes. Alterations of membrane sterol composition perturb the execution of cell division, which in diverse eukaryotes can have severe consequences for development of the organism. Partitioning of the cytoplasm during cell division occurs at the final stage of cell division named cytokinesis. LÄS MER