Sökning: "Th3"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet Th3.

  1. 1. On cellular immunology in chronic idiopathic thrombocytopenic purpura (ITP)

    Författare :Per-Ola Andersson; Göteborgs universitet; []
    Nyckelord :chronic ITP; T-cells; TGF-b1; Th3; cell-mediated cytotoxicity; KIR; DNA microarray;

    Sammanfattning : Chronic idiopathic thrombocytopenic purpura (ITP) is an acquired autoimmune disease characterized by a low platelet count and mucocutaneous bleedings. Chronic ITP is considered to be mediated by autoantibodies leading to premature destruction of platelets in the reticuloendothelial system. LÄS MER

  3. 2. Studies of Mucosal Immune Regulation in Celiac Disease and Type 1 Diabetes

    Författare :Anne Lahdenperä; Johnny Ludvigsson; Outi Vaarala; Rosaura Casas; Eva Sverremark-Ekström; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Background: Celiac disease (CD) and type 1 diabetes (T1D) are two chronic autoimmune diseases with increasing incidence worldwide. A combination of genetic, environmental and immunological factors is considered to be involved in development of the diseases, even though the exact disease mechanisms still are unknown. LÄS MER

  4. 3. Immunoregulation in experimental autoimmune myasthenia gravis

    Författare :Hua-Bing Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Myasthenia gravis (MG) derives its name from Latin and Greek words meaning, "grave muscle weakness". MG is a classical T cell dependent antibody-mediated autoimmune disease. LÄS MER

  5. 4. Immune mechanisms in atherosclerosis : the role of T cells in murine models of atherosclerosis

    Författare :Xinghua Zhou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :atherosclerosis; inflammation; murine models; low density lipoprotein; lipoprotein oxidation; T lymphocyte; T-cell antigen receptors; hypercholesterolemia; autoantibodies; T-cell cytokines; immunization; cardiolipin;

    Sammanfattning : Atherosclerosis is an inflammatory disease. Much interest has been focused on the immune responses in the pathogenesis of the disease. The role of T cells in the development of atherosclerosis was therefore investigated in murine models in this study. LÄS MER

  7. 5. Aspects of the Pre-Diabetic Period in Type 1 Diabetes

    Författare :Linda Åkerman; Rosaura Casas; Johnny Ludvigsson; Susan Wong; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Type 1 diabetes (T1D) is an autoimmune disease characterized by insulin deficiency, due to immune-mediated destruction of beta cells. Current knowledge regarding the period preceding disease onset comes, to a large extent, from studying risk cohorts based on relatives of T1D-patients, as they have an increased disease risk. LÄS MER