Sökning: "hypercholesterolemia"
Visar resultat 1 - 5 av 57 avhandlingar innehållade ordet hypercholesterolemia.
1. High Blood Cholesterol. Physician and Patient Perspectives
Sammanfattning : Scientific evidence of the causal relationship between high blood cholesterol and risk for coronary heart disease prompted extensive professional and public interest in practical application in the 1980's. Among other things, national guidelines for lipid lowering were published in Sweden in 1988. Mass media covered the topic extensively. LÄS MER
2. Ethnic heterogeneity of the North-Swedish population : its origin and medical consequences
Sammanfattning : Northern Sweden shows a unique population structure with remarkable geographical variations in the distribution of genetic disorders as well as genetic markers like blood groups, serum groups and red cell enzyme types. The present-day population of northern Sweden is a mixture of people of Finnish, Saamish (Lappish) and Central-Swedish origin. LÄS MER
3. Cardiovascular risk factors in aortic stenosis
Sammanfattning : Introduction: Aortic stenosis (AS) is the most common hemodynamic significant valvular heart disease and affects about 2% of the population. The incidence increases with age. When symptoms of the stenotic aortic valve disease eventually occur the 2-year mortality exceeds 50%. LÄS MER
4. Familial hypercholesterolemia in Sweden : genetic and metabolic studies
Sammanfattning : Familial hypercholesterolemia (FH) is inherited as an autosomal codominant disease, usually caused by mutations in the LDL receptor (LDLR) gene. Heterozygous FH is a common disease with a prevalence of about 1/500 in most populations. Clinically, FH is characterized by elevated LDL cholesterol, tendon xanthomas and premature atherosclerosis. LÄS MER
5. Mutation Analysis and Hypercholesterolemia: Studies in FH patients and in healthy middle-aged men with high, low, or increasing cholesterol levels during a six-year follow-up (the CRISS study)
Sammanfattning : Our aims were to characterize familial hypercholesterolemia (FH) in a Swedish FH population and to further elucidate the clinical expression and treatment response in relation to genotype. Secondly, we wanted to identify gene variants, which may have impact on cholesterol levels in apparently healthy subjects. LÄS MER