Sökning: "Rolf Kiessling"
Hittade 3 avhandlingar innehållade orden Rolf Kiessling.
1. Immunogene Therapy of Bladder Carcinoma : A Preclinical Study
Sammanfattning : This thesis comprises studies on murine and human models of bladder carcinoma with the aim to develop novel immunogene therapies. On the basis of the results presented in this thesis, a clinical trial is underway. The potential of activating the immune system to combat cancer has long intrigued immunologists. LÄS MER
2. Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy
Sammanfattning : This thesis concerns the investigation of novel immunotherapies for cancer eradication. CpG therapy was used in order to target antigen-presenting cells (APCs), facilitating antigen presentation and activation of T cells. LÄS MER
3. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization
Sammanfattning : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. LÄS MER