Sökning: "Purkinje cells"

Visar resultat 11 - 15 av 22 avhandlingar innehållade orden Purkinje cells.

  1. 11. Cerebellar development and very preterm birth interactions with neonatal events

    Författare :Kristbjorg Sveinsdottir; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : AbstractThe cerebellum is an important part of the brain and in very preterm infants the cerebellum is smaller at term equivalent age compared to that of infants born at term.Hypothesis and aims: The general hypothesis is that preterm birth per se causes cerebellar underdevelopment and that certain events following preterm birth, either complications or treatments, can aggravate the underdevelopment. LÄS MER

  3. 12. From molecule to neuron : thyroid hormone action in the brain

    Författare :Susi Gralla; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The importance of thyroid hormone (TH) for mental health has been known for decades. With the identification of the thyroid hormone receptors α and β (TRα, TRβ), TR dependent mechanisms involved in brain development were investigated, identifying TRα1 as the main TR isoform in the brain. LÄS MER

  4. 13. Novel Interactors of X-linked Inhibitor of Apoptosis Protein : Expression and Effects on Tumor Cell Death

    Författare :Håkan Steen; Dan Lindholm; Bertrand Joseph; Uppsala universitet; []
    Nyckelord :Neurobiology; XIAP; tumor cell death; apoptosis; caspases; basic helix-loop-helix protein; Neurobiologi;

    Sammanfattning : Programmed cell death, or apoptosis, has during the last decade received a lot of attention due to its involvement in a large number of pathological conditions. Since death is always irreversible, it is important for cells to fully control the initiation and execution of this process. LÄS MER

  5. 14. The muscle cytoskeleton of mice and men : Structural remodelling in desmin myopathies

    Författare :Lena Carlsson; Lars-Eric Thornell; Anders Arnér; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; desmin; nestin; synemin; paranemin; plectin; αB-crystallin; skeletal muscle; heart muscle; myotendinous junction; motor endplate; costamere; anatomi; Human Anatomy;

    Sammanfattning : The muscle fibre cytoskeleton of skeletal and heart muscle cells is composed mainly of intermediate filaments (IFs), that surround the myofibrils and connect the peripheral myofibrils with the sarcolemma and the nuclear membrane. Desmin is the first muscle specific IF protein to be produced in developing muscles and is the main IF protein in mature muscles. LÄS MER

  7. 15. Expression and function of thyroid hormone receptor alpha 1 in the brain

    Författare :Karin Wallis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Thyroid hormone is fundamentally important for development and maintenance of adult brain functions and maternal hypothyroxinemia during pregnancy can lead to a severe mental retardation known as endemic cretinism. The first realization that endemic cretinism is caused by iodine deficiency and its association with thyroid hormone was made a century ago; this eventually resulted in dietary supplementation programme, e. LÄS MER