Sökning: "Proportional Hazards"

Visar resultat 6 - 10 av 77 avhandlingar innehållade orden Proportional Hazards.

  1. 6. Semiparametric survival models for routine register data

    Författare :Frank Eriksson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Survival; transformation; clustered; likelihood; random effects; case-cohort; routine register; semiparametric; clustered;

    Sammanfattning : Routine registers offer researchers opportunities to carry out studies of covariate effects on lifetimes of rare diseases otherwise infeasible because of the large cohorts required. Familial relationships necessary for analysis of environmental or genetic factors can be identified by record linking. LÄS MER

  3. 7. Modelling short and long term consequences of changes in diagnostic activity and treatment

    Författare :Marcus Westerberg; Rolf Larsson; Hans Garmo; Pär Stattin; Keith Humphreys; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mathematics prostate cancer statistics diagnostic activity; Statistics; Statistik; Epidemiologi; Epidemiology; Mathematics with specialization in Applied Mathematics; Matematik med inriktning mot tillämpad matematik;

    Sammanfattning : Since the late 90’s the diagnostic activity for prostate cancer has increased in Sweden, primarily due to increased use of PSA testing, and this has led to a large increase in diagnoses. Simultaneously, there have been changes in treatment strategies, and more effective treatments have been introduced. LÄS MER

  4. 8. Prediction-driven decision rules, RCT design and survival analysis

    Författare :Adam Brand; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Predictions are becoming more and more a part of our lives, and they are becoming increasingly useful in medical science as the science evolves. Increased understanding of disease and its treatments allows us to use predictions based on predictive biomarker signatures to optimize treatment outcomes for increasingly granular subject groups. LÄS MER

  5. 9. Chronic obstructive pulmonary disease: exacerbations and mortality : Prognostic value of biomarkers and comorbidities

    Författare :Jens Ellingsen; Andrei Malinovschi; Christer Janson; Arnulf Langhammer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COPD; exacerbations; mortality; biomarkers; comorbidity; Lungmedicin; Lung Medicine;

    Sammanfattning : Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality. COPD is associated with systemic inflammation, and comorbidities are common. A characteristic feature is acute exacerbations (AECOPDs), i.e. LÄS MER

  7. 10. Hypertension, atherosclerosis and fracture risk - observational investigations with focus on antihypertensive therapy

    Författare :Tove Bokrantz; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epidemiology; hypertension; antihypertensive agents; fractures; peripheral arterial disease; bone density;

    Sammanfattning : Aim: To investigate associations between hypertension, arteriosclerotic disease, and fracture risk in adults and the elderly, with a certain focus on how specific antihypertensive drug treatments in patients with high blood pressure might affect the risk for fractures. Methods and results: In Study I and II, the associations between different antihypertensive treatments and fracture risk were investigated in a cohort of about 60. LÄS MER