Sökning: "Neural Probes"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden Neural Probes.

  1. 1. Development of a polymer based neural probe - How to record intracortical neural activity while minimizing the tissue response

    Författare :Fredrik Ejserholm; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Neural Probes; Electrode Modification; Polymer; Neurophysiology; OSTE ;

    Sammanfattning : Intracortical neural probes have in the last couple of years been developed from stiff single probes to stiff multi-electrode neural probes to flexible multi-electrode neural probes. One reason for the change in design is that more than one recording/stimulation electrode, as in the case with a single wire, is needed for more advanced studies. LÄS MER

  3. 2. A tailored biocompatible neural interface for long term monitoring in neural networks

    Författare :Per Köhler; Neuronano Research Center (NRC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain-machine interfaces; neuroinflammation; somatosensory cortex; hyperalgesia; allodynia;

    Sammanfattning : Neural interface electrodes that can record from neurons in the brain for long periods of time will be of great importance to unravel how the brain accomplishes its functions. However, current electrodes usually cause significant glia reactions and loss of neurons within the adjacent brain parenchyma. LÄS MER

  4. 3. A novel implantable ultra-flexible brain machine interface. Manufacturing and initial characterisations

    Författare :Fotios Tsanakalis; Neuronano Research Center (NRC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain-Machine Interfaces; BMIs; Neural Interfaces; Electrodes;

    Sammanfattning : This thesis describes for the very first time the development of a miniaturized neural interface which is flexible in three dimensions (3D) to enable it to follow the brain movements with minimal dislocation. Both the design rationale and the material choice for the electrodes aim to develop interfaces that minimize the damage and/or the irritation of the tissue during and after the implantation. LÄS MER

  5. 4. Microenvironmental control and molecular detection of neural stem cell state and fate

    Författare :Shirin Ilkhanizadeh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neural stem cell growth and specialization is dependent on microenvironmental cues, such as growth factors, oxygen levels and substrate stiffness. Together these cues define the genetic and epigenetic program of neural stem cells. In our studies we have manipulated these cues in order to achieve better control of neural stem cell state and fate. LÄS MER

  7. 5. Epigenetic and bioelectronic tools to study neural stem cells in health and disease

    Författare :Christina Neofytou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Brain development is a highly controlled, complex, and dynamic process. The mechanisms of its control need to accommodate the constantly changing contexts which, overtime, support the emergence of new neural structures and functions. LÄS MER