Sökning: "Ingrid Strömberg"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Ingrid Strömberg.

  1. 1. On dopamine neurons : nerve fiber outgrowth and L-DOPA effects

    Författare :Sara af Bjerkén; Ingrid Strömberg; Kathy Steece-Collier; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; nerve fiber outgrowth; astrocytes; ventral mesencephalon; GDNF; L-DOPA; L-DOPA induced dyskinesia; Neurobiology; Neurobiologi;

    Sammanfattning : Parkinson’s disease is a disorder mainly characterized by progressive degeneration of dopamine producing neurons in the substantia nigra of the midbrain. The most commonly used treatment strategy is to pharmacologically restore the lost function by the administration of the dopaminergic precursor L-DOPA. LÄS MER

  2. 2. Experimental Studies of BMP Signalling in Neuronal Cells

    Författare :Susanna Althini; Ted Ebendal; Carl-Henrik Heldin; Ingrid Strömberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Bone Morphogenetic Protein BMP ; Growth Differentiation Factor 10 GDF10 ; Aktivne-receptor Like Kinase 2 ALK2 ; Tyrosine Hydroxylase TH ; Neurotrophic Factor; Neurite Outgrowth; Hippocampus; Catecholamine; PC12; Sympathetic Ganglia; Substantia Nigra SN ; Gene Targeting; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; Medicinsk utvecklings- och neurobiologi;

    Sammanfattning : The developing nervous system depends largely on extracellular cues to shape its complex network of neurons. Classically, neurotrophins are known to be important mediators in this process. LÄS MER

  3. 3. Dopamine neurons in ventral mesencephalon : interactions with glia and locus coeruleus

    Författare :Elisabet Berglöf; Ingrid Strömberg; Stephen B. Dunnett; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; ventral mesencephalon; nerve fiber formation; glia; locus coeruleus; grafting; antioxidant-enriched diet; Histology; Histologi;

    Sammanfattning : Parkinson’s disease is a progressive neurodegenerative disorder, characterized by a depletion of the dopaminergic neurons in the substantia nigra. The cause of the disease is yet unknown but age, oxidative stress, and neuroinflammation are some of the features involved in the degeneration. LÄS MER

  4. 4. GDNF and alpha-synuclein in nigrostriatal degeneration

    Författare :Maria Chermenina; Ingrid Strömberg; Guido Nikkhah; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; GDNF; ventral mesencephalon; lateral ganglionic eminence; alpha-synuclein; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences;

    Sammanfattning : Parkinson’s disease is a common neurological disorder with a complex etiology. The disease is characterized by a progressive loss of dopaminergic cells in the substantia nigra, which leads to motor function and sometimes cognitive function disabilities. LÄS MER

  5. 5. Interaction between nerve fiber formation and astrocytes

    Författare :Sanazalsadat Hashemian; Ingrid Strömberg; Elisabet Åkesson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; nerve fiber outgrowth; astrocytes; ventral mesencephalon; spinal cord; CSPG; CD47;

    Sammanfattning : Parkinson’s disease, the second most common neurodegenerative disorder,is characterized by loss of nigrostriatal dopaminergic neurons. To date,there is no defined cause and cure for the disease. An ideal treatmentstrategy is to replace the lost neurons by transplanting fetal dopaminergicneurons to the brain of parkinsonian patients. LÄS MER