Sökning: "IGFBP-3"

Visar resultat 1 - 5 av 23 avhandlingar innehållade ordet IGFBP-3.

  1. 1. Early growth, retinopathy of prematurity and insulin-like growth factors in preterm infants

    Författare :Eva Engström; Göteborgs universitet; []
    Nyckelord :Preterm; ROP; nutrition; growth; growth restriction; IGF-I; IGF-II; IGFBP-3;

    Sammanfattning : Aims:Paper I: To perform measurements of the lower leg length (LLL) in preterm infants, compare and evaluate handling error and precision of two instruments, and estimate the time required to show growth.Paper II-IV: To investigate whether low postnatal levels of serum IGF-I are associated with abnormal retinal vessel development. LÄS MER

  3. 2. Novel insulin-like growth factor-binding protein proteases : detection and characterization

    Författare :Jing Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :IGFs; IGFBP-1. IGFBP-3; azurocidin HBP CAP37; IGFBP protease; gender;

    Sammanfattning : Members of the insulin-like growth factor (IGF) system are known to have an impact on cell differentiation, proliferation and survival, and to be important regulators for nutrient metabolism. The IGF-binding proteins (IGFBP-1 to -6) control the availability of IGFs (IGF-I and IGF-II) to their receptors. LÄS MER

  4. 3. Diabetes and puberty : studies on hormonal factors of importance to the blood glucose control

    Författare :Ingmar Zachrisson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 1 diabetes; Puberty; Adolescence; Metabolic Control; IGF-I; IGFBP-1; IGFBP-3; Proteases; Leptin;

    Sammanfattning : It is well known that, in children with type 1 diabetes, metabolic control often deteriorates during puberty. Better understanding of the mechanisms that cause deterioration of blood glucose control can lead to improved therapeutic approaches. LÄS MER

  5. 4. Autocrine and paracrine regulation of Leydig cell survival in the postnatal testis

    Författare :Eugenia Colón; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :IGFs; steroidogenesis; Leydig cells; steroidogenic acute regulatory protein StAR ; insulin; IGFBP-3; IGFBP-2 and steroidogenic enzymes;

    Sammanfattning : The primary function of testicular Leydig cells is the production of androgens that promote sexual differentiation in the fetus, secondary sexual maturation at the. time of puberty, and spermatogenesis in the adult. LÄS MER

  7. 5. Insulin-like growth factor binding protein-3 : structure and function

    Författare :Maria Ahlsén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Insulin-like growth factor (IGF) -I and -II share structural homology with insulin. Their receptors and intracellular signaling are similar. Consequently, the biological actions of IGFs and insulin are overlapping. Insulin is secreted on demand depending on e. LÄS MER