Sökning: "Glutaredoxin"

Visar resultat 1 - 5 av 35 avhandlingar innehållade ordet Glutaredoxin.

  1. 1. Isoforms of mammalian glutaredoxin 2

    Författare :Christoph Hudemann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Iron-sulfur proteins are characterized by the presence of iron-sulfur clusters containing sulfide linked iron centers in variable oxidation states. Glutaredoxins (Grx) are, among other redoxins, increasingly recognized to be involved at the interface between redox regulation, iron metabolism and iron-cluster biosynthesis. LÄS MER

  2. 2. In vivo functions of mammalian glutaredoxin 2

    Författare :Maria Lönn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Oxygen is essential for all respirating life forms. However, the use of molecular oxygen as terminal electron acceptor of the respiratory electron chain leads to the generation of reactive oxygen species (ROS) as product of incomplete oxygen reduction. To different extends, ROS can react with and damage DNA, lipids and proteins. LÄS MER

  3. 3. Molecular dynamics modelling of bacteriophage T4 glutaredoxin : assessing structural stability: computer simulation experiments and their comparison with X-ray diffraction data

    Författare :Olle Nilsson; Stockholms universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  4. 4. Thioredoxin and glutaredoxin systems under oxidative and nitrosative stress

    Författare :Xiaoyuan Ren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Our knowledge about reactive oxygen species (ROS) and reactive nitrogen species (RNS) has been changed from simple damaging molecules to redox signaling mediators. ROS/RNS mediated signaling is mainly based on the reversible post-translational modifications of cysteine which works as a switch for protein functions. LÄS MER

  5. 5. Regulation of human thioredoxin and glutaredoxin systems by oxidation and S-nitrosylation

    Författare :Seyed Isaac Hashemy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The homeostasis of intracellular redox status has a crucial role in the cell survival and different processes such as DNA synthesis, gene expression, enzymatic activity, etc. This homeostasis is achieved via an intense balance between pro-oxidants and anti-oxidants. LÄS MER