Sökning: "Gianluigi Forloni"
Hittade 2 avhandlingar innehållade orden Gianluigi Forloni.
1. Altered cell signaling linked to neurodegeneration : Studies on scrapie-infected neuroblastoma cells and activated microglia
Sammanfattning : Prion diseases are neurodegenerative disorders that can affect humans and animals. The underlying event is a conformational change of the normal cellular prion protein (PrPC) into an aberrant isoform termed PrP-scrapie (PrPSc). PrPSc is thought to lead to neurodegeneration and activation of glial cells. LÄS MER
2. On inflammatory cytokines and β-amyloid peptides in acute and chronic neurodegeneration
Sammanfattning : Insults to the brain as well as neurodegenerative diseases are known to elicit inflammatory responses. Inflammation in the brain can on one hand initiate processes that are harmful to the injured tissue and exacerbate the damage, leading to neuronal degeneration and glial activation, and on the other hand activate processes that may be necessary for repair mechanisms and regeneration. LÄS MER