Sökning: "Fredrik Asplund"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Fredrik Asplund.

  1. 1. Risks Related to the Use of Software Tools when Developing Cyber-Physical Systems : A Critical Perspective on the Future of Developing Complex, Safety-Critical Systems

    Författare :Fredrik Asplund; Martin Törngren; Jad El-Khoury; John McDermid; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Automation; Certification; Process Risks; Safety; Safety-Critical; Standards; Support Environments; Tool Integration; Machine Design; Maskinkonstruktion;

    Sammanfattning : The increasing complexity and size of modern Cyber-Physical Systems (CPS) has led to a sharp decline in productivity among CPS designers. Requirements on safety aggravate this problem further, both by being difficult to ensure and due to their high importance to the public. LÄS MER

  3. 2. Tool Integration and Safety : A Foundation for Analysing the Impact of Tool Integrationon Non-functional Properties

    Författare :Fredrik Asplund; Martin Törngren; Jad El-khoury; Jakob Axelsson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Tool Integration; Integrated Development Environments; Embedded Systems; Safety Standards; Certification; Qualification; Systems Thinking; System Safety; STAMP; STPA;

    Sammanfattning : The increasing complexity of embedded systems development is becoming difficult to handle with development environments based on disjoint engineering tools. Support for interactions between various engineering tools, especially through automated means, has therefore received an increased amount of attention during the last few years. LÄS MER

  4. 3. Molecular Analysis of Normal Human Skin and Basal Cell Carcinoma Using Microdissection Based Methods

    Författare :Anna Asplund; Fredrik Pontén; Uffe Birk Jenssen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; skin; basal cell carcinoma; microdissection; X-chromosome inactivation; Patologi; Pathology; Patologi;

    Sammanfattning : The aim of this thesis was to gain further insight into the biology of normal human skin and basal cell carcinoma (BCC). Morphology in combination with microdissection was used as primary tool for sampling. LÄS MER

  5. 4. Resource Optimized Stereo Matching in Reconfigurable Hardware for Autonomous Systems

    Författare :Fredrik Ekstrand; Lars Asplund; Rafael Garcia; Mälardalens högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; elektronik; Electronics;

    Sammanfattning : There is a need for compact, high-speed, and low-power vision systems for enabling real-time mobile autonomous applications. The best approach to achieve this is to implement the bulk of the application in hardware. LÄS MER

  7. 5. Validation of antibodies for tissue based immunoassays

    Författare :Sandra Andersson; Anna Asplund; Fredrik Pontén; Kenneth Wester; Mike Taussig; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibody validation; Conjugation; Estrogen receptor-beta; IHC; ISH; Lymphohematopoietic tissues; Proteomic; RNAseq; TMA; Transcriptomic; Patologi; Pathology;

    Sammanfattning : In situ protein detection in human tissues using antibodies reveals the cellular protein localization, and affinity-based proteomic studies can help to discover proteins involved in the development of diseases. However, antibodies often suffer from cross-reactivity, and the lack of positive and negative tissue controls for uncharacterized proteins complicates the mapping of the proteome. LÄS MER