Sökning: "Extracellular fluid"

Visar resultat 6 - 10 av 151 avhandlingar innehållade orden Extracellular fluid.

  1. 6. Proteomic strategies for analysis of cerebrospinal fluid in neurodegenerative disorders

    Författare :Sara Folkesson Hansson; Göteborgs universitet; []
    Nyckelord :Alzheimer?s disease; frontotemporal dementia; cerebrospinal fluid; neurodegeneration; proteomics; mass spectrometry; prefractionation; protein identification; quantification;

    Sammanfattning : ABSTRACT There is a great need for biomarkers to diagnose neurodegenerative disorders, such as the cognitive disorders Alzheimer?s disease (AD) and frontotemporal dementia (FTD). Cerebrospinal fluid (CSF) is in contact with the extracellular fluid of the brain and is consequently a valuable medium for identifying biomarkers for neurological disorders. LÄS MER

  3. 7. Exosomes - characterisation of the RNA and protein cargo

    Författare :Cecilia Lässer; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astma; body fluid; breast milk; chronic rhinosinusitis; exosomes; extracellular vesicles; nasal lavage; plasma; proteomics; RNA; saliva;

    Sammanfattning : .... LÄS MER

  4. 8. Signaling to the immature brain - Choroid plexus, insulin-like growth factor 1 and extracellular vesicles

    Författare :Niklas Ortenlöf; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IGF-1; Choroid plexus; Immature brain; Extracellular vesicle; CSF; Preterm infants;

    Sammanfattning : Extremely preterm infants (i.e., born below 28 gestational weeks), are at high risk of developing brain morbidities including intraventricular hemorrhage (IVH) and neurodevelopmental impairment. Despite over 50 years of research, there is currently no effective therapy available for preventing IVH. LÄS MER

  5. 9. Intra- and Extracellular Modulation of Integrin-directed Connective Tissue Cell Contraction

    Författare :Tijs van Wieringen; Kristofer Rubin; Anders Arner; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Interstitial fluid pressure; PDGF-BB; bacterial proteins; αVβ3 integrin; cytoskeleton; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : All blood vessels in the microvasculature are embedded in loose connective tissue, which regulates the transport of fluid to and from tissues. The intersti-tial fluid pressure (IFP) is one of the forces that control this transport. LÄS MER

  7. 10. Interactions between extracellular matrix proteins and the complement system - In the perspective of cartilage degradation in inflammatory joint diseases

    Författare :Camilla Melin Fürst; Malmö Proteinkemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complement system; rheumatoid arthritis; osteoarthritis; extracellular matrix; cartilage degradation; mass spectrometry;

    Sammanfattning : Abstract: The joint diseases osteoarthritis and rheumatoid arthritis are characterized by destructive inflammatory processes that result in pathological changes of the joint tissues, including proteolytic degradation of cartilage and release of extracellular matrix proteins or fragments to the synovial fluid. The complement system, which is a part of the innate immune system, plays a central role in promoting the joint inflammation in these diseases. LÄS MER