Sökning: "Cyclooxygenase inhibitors"

Visar resultat 11 - 15 av 38 avhandlingar innehållade orden Cyclooxygenase inhibitors.

1. 11. Angiotensin converting enzyme inhibition and aspirin in congestive heart failure

   Författare :Tord Juhlin; Kardiologiska klinikens forskargrupp; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clinical trial; ARBs; renal function; congestive heart failure; ischaemic heart disease; NSAIDs; ACE-inhibitors; aspirin; dose dependency; Cardiovascular system; Kardiovaskulära systemet;

   Sammanfattning : Angiotensin-converting enzyme (ACE) inhibitors act by decreasing production of angiotensin II and by potentiating the effects of bradykinin by inhibition of its breakdown. Bradykinin exerts part of its effects via vasodilating prostaglandins. Since the cyclooxygenase (COX)-inhibitors, e.g. LÄS MER

3. 12. Studies on the Effects of Plant and Food Constituents on Cyclooxygenase-2 : Aspects in Inflammation and Cancer

   Författare :Ulrika Huss; Pia Wuorela; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacognosy; Farmakognosi; Pharmacognosy; Farmakognosi;

   Sammanfattning : In inflammatory events, the cyclooxygenase-2 enzyme (COX-2) catalyses prostaglandin biosynthesis. This is a process, which could possibly be affected by natural compounds including those abundant in food. Two systems have been established to enable investigations of the effects of natural compounds on COX-2. LÄS MER

4. 13. Integration of Tumor and Host Factors – Implications for Breast Cancer Prognosis

   Författare :Maria Simonsson; Tumörmikromiljö; []
   Nyckelord :Breast Cancer; Prognosis and survival; CYP1A2; CYP2C8; Coffee Consumption; Alcohol Consumption; Cyclooxygenase-2 COX-2 ;

   Sammanfattning : Breast cancer is the most common cancer among women worldwide, although the mortality rates have decreased in the last decades. Breast cancer is a heterogeneous disease, and treatment resistance is a significant clinical problem in spite of the overall high survival rates. LÄS MER

5. 14. An experimental study of mediators in allergic bronchoconstriction with focus on eicosanoids

   Författare :Ewa Selg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Leukotrienes; prostaglandins; histamine; guinea pig lung; ovalbumin; mast cell; cyclooxygenase; airway smooth muscle; COX inhibitors; NSAIDs;

   Sammanfattning : Mast cells have a central role in the inflammatory response in airways of both atopic and non-atopic asthmatics. The mast cell-derived mediators such as histamine, leukotriene C4 and prostaglandin D2, released upon activation of the cell, produce acute bronchoconstriction that is characteristic of the early asthmatic response (EAR), and contribute to the development of airway inflammation and hyperresponsiveness following the initial reaction. LÄS MER

7. 15. Prostanoids and colorectal cancer

   Författare :Annika Gustafsson Asting; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer prostanoid receptors cyclooxygenase PGE2 transcription factors;

   Sammanfattning : Tumor disease is a main cause of death in Western countries and a most common malignancy is colorectal cancer (CRC). Growing tumors are dependent on interactions among several different cells as well as signaling pathways. LÄS MER