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Visar resultat 1 - 5 av 17 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Optimizing Percutaneous Coronary Intervention

    Författare :Sofia Bergman; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Percutaneous Coronary Intervention; intravascular imaging; Intravascular ultrasound; Optical coherence tomography; near infrared spectroscopy; Intraprocedural stent thrombosis;

    Sammanfattning : .... LÄS MER

  2. 2. Prognostic impact of coronary microvascular funtion in patients with ischemic heart disease

    Författare :Inger Haraldsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary microvascular function; coronary flow reserve; coronary artery disease; acute coronary syndromes; thrombus aspiration; pretreatment; SCAAR; SWEDHEART;

    Sammanfattning : Background: Ischemic heart disease is the leading cause of death globally. Despite recent advances in interventional and medical therapies, survivors of myocardial infarction are at high risk of recurrent cardiovascular events. LÄS MER

  3. 3. Invasive treatment of coronary artery disease : Aspects on antithrombotic and percutaneous treatment options

    Författare :Per Grimfjärd; Stefan James; Christoph Varenhorst; P Hedberg; Lene Holmvang; Uppsala universitet; []
    Nyckelord :PCI; STEMI; stent thrombosis; bivalirudin; heparin; bioresorbable scaffold; cangrelor; drug eluting stent; DES; Cardiology; Kardiologi;

    Sammanfattning : The outcome after percutaneous coronary intervention (PCI) has improved considerably thanks to more effective antithrombotic treatment strategies and improved coronary stents. Stent thrombosis (ST) is a rare complication to PCI associated with considerable mortality and morbidity. LÄS MER

  4. 4. Platelet Inhibition in Coronary Artery Disease – Mechanisms and Clinical Importance : Studies with Focus on P2Y12 Inhibition

    Författare :Christoph Varenhorst; Stefan James; Agneta Siegbahn; Lars Wallentin; Steen Dalby Kristensen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary artery disease; myocardial infarction; acute coronary syndromes; stent thrombosis; P2Y12 inhibitors; thienopyridines; clopidogrel poor response; clopidogrel; prasugrel; Cardiology; Kardiologi; Kardiologi; Cardiology;

    Sammanfattning : Despite the currently recommended dual antiplatelet treatment (DAT) with aspirin and P2Y12 inhibition in patients with coronary artery disease (CAD) there is a risk of adverse clinical outcome. Pharmacodynamic (PD) poor response to clopidogrel occurs in ~ 30% of clopidogrel-treated patients and is associated with an increased risk of recurrent thrombotic events. LÄS MER

  5. 5. Coronary artery disease and prognosis in relation to cardiovascular risk factors, interventional techniques and systemic atherosclerosis

    Författare :Fredrik Calais; Ole Fröbert; Jerzy Leppert; Bo Lagerqvist; Stefan K James; Douwe E. Atsma; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Myocardial infarction; Coronary artery disease; Extra-cardiac artery disease; Coronary stent; Thrombus aspiration; physical inactivity; Prognosis;

    Sammanfattning : Aim: To evaluate the prognosis associated with location and severity of coronary and systemic atherosclerosis in patients with coronary artery disease (CAD) in relation to risk factors and interventional techniques.Methods: The thesis comprised six longitudinal studies based on three patient cohorts: The Swedish Coronary Angiography and Angioplasty Registry, the Västmanland Myocardial Infarction Survey, and the Thrombus Aspiration in ST-Elevation myocardial infarction in Scandinavia study, to evaluate clinical outcome relative to coronary lesion location and severity, extracoronary artery disease (ECAD), intervention techniques, and leisuretime physical inactivity (LTPI). LÄS MER