Sökning: "CHOP"

Visar resultat 1 - 5 av 23 avhandlingar innehållade ordet CHOP.

  1. 1. Molecular studies of genetic changes in myxoid and round cell liposarcoma

    Författare :Sofia Järnum; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; Cytologi; onkologi; cancer; Medicine human and vertebrates ; Medicin människa och djur ; oncology; Cytology; autocrine loop; RDA; persephin; RET; LEPREL1; translocation; fusion gene; liposarcoma; TLS; CHOP;

    Sammanfattning : Chromosomal translocations commonly result in the production of fusion genes and the fusion genes are often tumor-type specific. In myxoid and round cell liposarcomas (MLS/RCLS), almost 95% of the cases carry a t(12;16)(q13;p11). In the remaining 5% of the MLS/RCLS tumors, another translocation and fusion gene can be found, i.e. LÄS MER

  3. 2. Epidemiological and clinical aspects of T-cell lymphoma

    Författare :Henrik Cederleuf; Medicinsk onkologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; population-based; peripheral T-cell lymphoma; Anaplastic large cell lymphoma; angioimmunoblastic; elderly; ASCT; comorbidity; prognostic factors; follow-up; limited stage; etoposide; CHOP; overall survival; radiotherapy;

    Sammanfattning : T-cell lymphoma (TCL) is a rare group of malignancies and one of the important aims in this thesis has been to broaden the general knowledge of TCL with descriptive patient data. Main focus has been to examine prognosticfactors for overall survival (OS) and progression-free survival (PFS), and to evaluate different treatment approaches and follow-up (FU) after treatment. LÄS MER

  4. 3. Clinical and Molecular Studies of Diffuse Large B-cell Lymphoma

    Författare :Amal Abu Sabaa; Gunilla Enblad; Peter de Nully Brown; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DLBCL; R-CHOP; EFS24; PEA; Biomarker; ELISA; TCL1A.;

    Sammanfattning : The general aim of this thesis was to study the prognostic clinical and biological markers of Diffuse Large B-cell Lymphoma (DLBCL).Paper I: Utilizing population-based data for patients with DLBCL in Sweden, the study aimed to establish whether event free survival at 24 months (EFS24) was a reproducible milestone. LÄS MER

  5. 4. Clinical studies in aggressive non-Hodgkin's lymphoma with special reference to elderly patients

    Författare :Eva Ösby; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aggressive; non-Hodgkin s lymphoma; elderly; CHOP; mitoxantrone; etoposide; G-CSF; response evaluation; longevity;

    Sammanfattning : The age-adjusted incidence rate of non-Hodgkin´s lymphoma (NHL), in particular diffuse large B cell lymphoma, has increased continuously during several decades. Patients with aggressive NHL are potentially curable but the 5-year overall survival (OS) is still less than 50% in the whole group. LÄS MER

  7. 5. Prognostic Markers and Mechanisms of Chemotherapy Resistance in Diffuse Large B-cell Lymphoma

    Författare :Karin Fjordén; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Diffuse large B-cell lymphoma (DLBCL) is an aggressive and heterogeneous disease. Identification of prognostic and predictive markers is important to design individualised and effective treatment strategies. LÄS MER