Sökning: "CD25"
Visar resultat 6 - 10 av 75 avhandlingar innehållade ordet CD25.
6. CD4+CD25+ T regulatory cells in multiple sclerosis
Sammanfattning : Multiple sclerosis (MS) is a chronic, inflammatory, and demyelinating disease of the central nervous system (CNS), which is likely to be mediated by autoaggressive immunity. Treatments of MS that may beneficially influence the disease course consist of Avonex (interferon-beta; IFN-beta), and Copaxone (glatiramer acetate; GA). LÄS MER
7. CD25+CD4+ regulatory T cells in rheumatic disease
Sammanfattning : CD25+CD4+ T cells represent a unique cell lineage of thymus derived naturally occurring regulatory T cells. The gene Foxp3 (mouse)/ FOXP3(human) is strictly related to their generation in the thymus and their regulatory function in the periphery. LÄS MER
8. Phenotype and function of CD25+ regulatory T cells in infants and adults
Sammanfattning : Active suppression by CD4+CD25+FOXP3+ regulatory T cells (Treg) is essential for the maintenance of peripheral tolerance to both self antigens and environmental antigens. Absence of these cells in human newborns leads to autoimmune and inflammatory disorders as well as allergic disease. LÄS MER
9. Studies on the function of CD4CD25 regulatory T cells: An in vitro approach
Sammanfattning : Immunological self-tolerance is a state of the whole organism where deleterious responses are either avoided or regulated. Breaking of immunological tolerance will lead to autoimmune disease or chronic inflammatory conditions. LÄS MER
10. Inhibition of T cell responses to autoantigens and allergens by CD25+ regulatory T cells from thymus, cord and adult blood
Sammanfattning : Autoimmune diseases and allergies are a growing problem in the western world today. Tolerance is primarily established by clonal deletion in the thymus. Despite this auto-reactive T cells are normally present in most individuals, which suggests that mechanisms of peripheral tolerance operate to silence potentially pathogenic T cells. LÄS MER