Sökning: "Anna Kauppi"

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1. 1. Chemical attenuation of bacterial virulence : small molecule inhibitors of type III secretion

   Författare :Anna Kauppi; Mikael Elofsson; Anders Karlén; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistance; virulence; type III secretion; T3SS inhibitors; Yop; SMD; QSAR; screening; Yersinia pseudotuberculosis; Organic chemistry; Organisk kemi;

   Sammanfattning : Despite the large arsenal of antibiotics available on the market, treatment of bacterial infections becomes more challenging in view of the fact that microbes develop resistance against existing drugs. There is an obvious need for novel drugs acting on both old and new targets in bacteria. LÄS MER