Sökning: "Alexandra Haara Löfstedt"

Hittade 1 avhandling innehållade orden Alexandra Haara Löfstedt.

1. 1. Hemophagocytic lymphohistiocytosis and associations with malignancies

   Författare :Alexandra Haara Löfstedt; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : In immune homeostasis, natural killer cells and cytotoxic T cells are responsible for clearance of virus-infected and tumor transformed cells, but also for turning off the immune response. Patients with familial hemophagocytic lymphohistiocytosis (HLH) have impaired cytotoxic function due to genetic aberrations in genes in the perforindependent cytotoxic pathway. LÄS MER