Sökning: "AT 2 receptor"

Visar resultat 1 - 5 av 1069 avhandlingar innehållade orden AT 2 receptor.

  1. 1. Galanin receptor ligands

    Författare :Johan Runesson; Ülo Langel; Lena Mäler; Stockholms universitet; []
    Nyckelord :Galanin; GALP; GPCR; Agonist; GalR; Chimeric peptide; Inositol phosphate production; Receptor specificity; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Sammanfattning : In the nervous system galanin primarily displays a modulatory role. The galaninergic system consists of a number of bioactive peptides with a highly plastic expression pattern and three different receptors. The lack of receptor subtype selective ligands and antibodies have severely hampered the charac-terization of this system. LÄS MER

  3. 2. Studies of a Proteinase-activated Cell Surface Receptor

    Författare :Sverker Nystedt; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; receptor; proteinase; PAR-2; molecular cloning; in situ hybridisation; Expression; G-protein; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : The G protein-coupled receptors form one of the largest families of proteins involved in signalling between cells. It contains receptors for molecules as diverse as biogenic amines, glycoproteins and enzymes. The manuscripts included in this thesis together describe the initial characterisation of a previously unknown receptor of this class. LÄS MER

  4. 3. Aspects of proteinase-activated receptor-2: A sensor of enzymatic activity at the cell surface

    Författare :Anna-Karin Alm; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsychology; Neurology; endometrium.; coagulation; signalling; proteinase; G-protein; cell; receptor; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Information about extracellular proteolytic activity is transduced to the cell by a transmembrane G-protein coupled receptor subfamily. These receptors are activated by proteolytic cleavage in the extracellular amino-terminal domain and are thus termed proteinase-activated receptors (PARs). LÄS MER

  5. 4. Neurosteroids Induce Allosteric Effects on the NMDA Receptor : Nanomolar Concentrations of Neurosteroids Exert Non-Genomic Effects on the NMDA Receptor Complex

    Författare :Tobias Johansson; Fred Nyberg; Pierre Le Grevès; Elisabeth Hansson; Uppsala universitet; []
    Nyckelord :Pharmaceutical pharmacology; Pharmacology; neurosteroids; NMDA receptor; NR2B subunit; ifenprodil; sigma receptor; anabolic androgenic steroids; allosteric modulation; non-genomic; Farmaceutisk farmakologi;

    Sammanfattning : The neurosteroids constitute a group of powerful hormones synthesized and acting in the central nervous system. They participate in a number of important central processes, such as memory and learning, mood and neuroprotection. LÄS MER

  7. 5. Psychosocial stress in relation to blood pressure and cardivascular disease - epidemiological and genetic aspects

    Författare :Bertil Öhlin; Internmedicin - epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; receptor; Cardiovascular system; Medicin människa och djur ; Medicine human and vertebrates ; adrenergic; alpha-2; beta-1; mortality; morbidity; prospective; studies; polymorphism; work; stress; blood pressure; hypertension;

    Sammanfattning : Psychosocial stress has been linked to both hypertension and cardiovascular disease (CVD), and hypertension has been proposed to be one mediator of the increased CVD risk in subjects reporting stress. Genetic susceptibility for blood pressure elevation in relation to stress has been proposed, but so far there is little evidence. LÄS MER