Sökning: "5-HT3 receptor"

Visar resultat 6 - 10 av 12 avhandlingar innehållade orden 5-HT3 receptor.

  1. 6. Functional Models in the Search for Pharmacological Treatment of Urinary Incontinence : The Role of Adrenergic, Cholinergic, and Serotonergic Receptors

    Författare :Ali-Reza Modiri; Karl-Erik Andersson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Stress incontinence and overactive bladder are disorders with a common symptom, urinary incontinence, which is a serious medical and social handicap. Several neurotransmitters regulate the function of the lower urinary tract, including noradrenaline, acetylcholine, and serotonin. LÄS MER

  3. 7. Novel insights into the role of serotonin in control of β-cell fuction

    Författare :Hedvig Bennet; Celiaki och diabetes; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Inadequate insulin secretion is a central component in the development of Diabetes Mellitus, resulting from reduced pancreatic β-cell mass, as well as diminished β-cell function. Islet produced 5-hydroxy tryptamine (5-HT) is suggested to regulate insulin secretion and β-cell mass in rodents during pregnancy and in metabolically challenged states. LÄS MER

  4. 8. Biomarkers in chronic and experimental human muscle pain

    Författare :Sofia Louca Jounger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :5-HT;

    Sammanfattning : The main aim of this thesis was to improve the knowledge ofthe peripheral mechanisms that may participate in the underlying pathophysiology of chronic temporomandibular disorders (TMD) myalgia i.e. pain that is experienced locally in the jaw muscles and has myofascial trigger points. LÄS MER

  5. 9. The role of nitric oxide in the gastrointestinal tract

    Författare :Linda Gillberg; Per Hellström; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nitric oxide (NO) is an important second messenger involved in the regulation of a multitude of mechanisms in the body, such as neurotransmission, smooth muscle contractility, host defense and immune regulation. Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are chronic disorders affecting the gastrointestinal (GI) tract with unknown etiology. LÄS MER

  7. 10. Temporomandibular joint involvement by systemic inflammatory disease with reference to pain modulation and joint tissue destruction

    Författare :Ülle Voog; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acute phase proteins; Computed tomography; Cytokines; Granisetron; Inflammation; Pain; Serotonin; Temporomandibular joint; Visual Analogue Scale.;

    Sammanfattning : Systemic inflammatory diseases may cause progressive destruction in the temporo-mandibular joint (TMJ). Involvement of this joint is associated with many clinical signs and symptoms of which pain is a major problem. LÄS MER