Sökning: "Jeremy Bost"

Hittade 1 avhandling innehållade orden Jeremy Bost.

1. 1. Characterizing and exploiting the endocytic pathway for macromulecular delivery

   Författare :Jeremy Bost; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Macromolecular drugs with cytosolic or nuclear targets often exhibit low therapeutic activity due, at least in part, to their inability to escape endosomal compartments following cellular internalization. There exist a range of strategies to address this inefficient delivery by attempting to bolster the endosomal escape of the therapeutic cargo. LÄS MER