Sökning: "thiamine"

Visar resultat 11 - 15 av 16 avhandlingar innehållade ordet thiamine.

  1. 11. Prostaglandin E2 as mediator and modulator of airway smooth muscle responses

    Författare :Jesper Säfholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostaglandin E2 (PGE2) is a lipid mediator produced by virtually every cell of the human body. Because common non-steroidal anti-inflammatory drugs (NSAIDs) inhibit its biosynthesis, PGE2 is usually considered to be a ‘pro-inflammatory’ mediator. The role of PGE2 in the lung and airways has however always been unclear. LÄS MER

  2. 12. Quantum Chemical Modelling of Enzymatic and Organometallic Reactions

    Författare :Ferran Planas; Fahmi Himo; Edina Rosta; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DFT; enzyme; organometallic; mechanisms; organisk kemi; Organic Chemistry;

    Sammanfattning : In this thesis, density functional theory (DFT) is employed in the study of two enzymes and two organometallic systems.First, the natural reaction mechanism, as well as the enantioselective formation of α-hydroxyketones catalysed by two thiamine diphosphate (ThDP)- dependent enzymes, namely benzoylformate decarboxylase (BFDC) and 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid (SEPHCHC)- synthase (MenD), are investigated. LÄS MER

  3. 13. Short-term adaptation of S. cerevisiae to lignocellulosic inhibitors: Underlying metabolic and physiological changes

    Författare :Marlous van Dijk; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; lignocellulosic inhibitor tolerance; second generation bioethanol; short-term adaptation; differential gene expression; industrial yeast strains;

    Sammanfattning : The limited tolerance of Saccharomyces cerevisiae (budding yeast) to inhibitors present in lignocellulosic hydrolysates is a major challenge in second-generation bioethanol production. Short-term adaptation of the yeast to lignocellulosic hydrolysates during cell propagation has been shown to improve its tolerance, and thus its performance in lignocellulose fermentation. LÄS MER

  4. 14. Evolutionary genomics of host-microbe interactions

    Författare :Elin Videvall; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; host; microbiota; avian malaria; ostrich; parasite; dual RNA-seq;

    Sammanfattning : The microbes living inside hosts have highly important consequences for host health and fitness. From the host’s perspective, some microbes exhibit mutualistic tendencies, others parasitic, and some commensal, but this is context-dependent and opportunistic lifestyles are widespread in nature. LÄS MER

  5. 15. Symbiosis in Arbuscular Mycorrhizal Fungi : Unearthing genomic signatures

    Författare :Shadi Eshghi Sahraei; Anna Rosling; Vasilis Kokkoris; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; arbuscular mycorrhizal fungi; mutualistic symbiosis; soil microeukaryotic communities; phylogenomics; single spore assembly; gene family evolution; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Arbuscular mycorrhizal (AM) fungi have been on earth since 470 million years ago. AM fungi form mutualistic symbiosis with most terrestrial plants and thus, are thought to have played important roles in land colonization together with plants. LÄS MER