Sökning: "structural proteins"

Visar resultat 1 - 5 av 922 avhandlingar innehållade orden structural proteins.

1. 1. Structural studies of proteins in apoptosis and lipid signaling

   Författare :Maria Dolores Herman Moreno; Pär Nordlund; Markus Gruetter; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; proteins; crystal structure; apoptosis; cancer; CoFi-Blot; kinases; lipid signaling; Structural biology; Strukturbiologi; Structural Biology; strukturbiologi;

   Sammanfattning : Signaling pathways control the fate of the cell. For example, they promote cell survival or commit the cell to death (apoptosis) in response to cell injury or developmental stimuli, decisions, which are vital for the proper development and functioning of metazoan. LÄS MER

3. 2. Fighting Tuberculosis – : Structural Studies of Three Mycobacterial Proteins

   Författare :Alina Castell; Torsten Unge; Manfred Weiss; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mycobacterium tuberculosis; Rv0216; Rv0130; Mycobacterium smegmatis; branched chain aminotransferase; X-ray crystallography; fatty acid metabolism; Structural biology; Strukturbiologi;

   Sammanfattning : This thesis presents the cloning, purification, crystallization, and structural studies of two unknown proteins from Mycobacterium tuberculosis, and of an aminotransferase from Mycobacterium smegmatis. Structural knowledge of these proteins is of highest interest for structure-based drug design, which is one of the approaches that can be used in order to fight tuberculosis (TB). LÄS MER

4. 3. Structural and Functional Studies of Gelsolin Family Proteins

   Författare :Qing Ma; Robert Robinson; Roger Karlsson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Structural biology; Strukturbiologi;

   Sammanfattning : The actin cytoskeleton is a complex structure that performs a wide range of cellular functions including: cell locomotion, cytokinesis, chemotaxis, signal transduction and apoptosis. The coordinated assembly and disassembly of actin filaments is controlled by a multitude of proteins (ABPs) in the cell. LÄS MER

5. 4. Structural studies of sugar binding proteins

   Författare :Sanjeewani Sooriyaarachchi; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Binding proteins, which are themselves non-enzymatic, play an important role in enzymatic reactions as well as non-enzymatic processes by providing a binding platform for the specific recognition of particular molecules. For example, periplasmic binding proteins play a vital role in nutrient uptake in Gram-negative bacteria. LÄS MER

7. 5. Visualizing structural dynamics: from small molecules to membrane proteins

   Författare :Magnus Andersson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; membrane protein; bacteriorhodopsin; proteorhodopsin; halorhodopsin; structural dynamics; time-resolved X-ray scattering;

   Sammanfattning : To fully understand the mechanism of a chemical reaction, it is important to characterize the rapid structural dynamics of transient chemical species as the reaction propagates. Since chemical processes are heavily influenced by the solvent in which they occur, the interaction with the surrounding solution also needs to be elucidated. LÄS MER