Sökning: "secondary-active transporter"

Hittade 3 avhandlingar innehållade orden secondary-active transporter.

  1. 1. Elucidating the molecular basis of Na+/H+ exchange

    Författare :Pascal F. Meier; David Drew; Simon Newstead; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane protein; secondary-active transporter; Solute Carrier Transporter; ion-exchange; sodium proton exchanger; potassium proton exchanger; protein structure; cryo-EM; regulation; biokemi; Biochemistry;

    Sammanfattning : Solute carrier (SLC) transporters are membrane transport proteins, which catalyse the movement of nutrients, ions, and drugs across cell membranes. Here, I will present our contribution to understanding the mechanism of the sodium/proton exchangers (NHE), belonging to the SLC9 family of membrane transporters. LÄS MER

  3. 2. Structure, Mechanism, and Regulation of Sodium/Proton Exchangers

    Författare :Iven Winkelmann; Drew David; Rajini Rao; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sodium proton exchange; SLC9; structure; secondary active transport; membrane protein; Biochemistry; biokemi;

    Sammanfattning : Sodium/proton exchangers (NHEs) are secondary active transporters that are ubiquitously found in all kingdoms of life. They facilitate the exchange of protons for sodium ions or other inorganic ions across biological membranes, regulating pH, sodium levels, and osmotic pressure. LÄS MER

  4. 3. Structural and functional studies of nutrient and drug uptake systems

    Författare :Fatma Guettou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Orally ingested nutrients and drugs are selectively absorbed from our small intestines into the bloodstream through various membrane-integrated transporters. The present study focuses mainly on a specific absorption route, namely the proton dependent oligopeptide transporters (POTs). LÄS MER