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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Novel Interventions in Cardiac Arrest : Targeted Temperature Management, Methylene Blue, S-PBN, Amiodarone, Milrinone and Esmolol,  Endothelin and Nitric Oxide In Porcine Resuscitation Models

   Författare :Frank Zoerner; Fredrik Lennmyr; Cécile Martijn; Lars Wiklund; Sven Erik Gisvold; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; restoration of spontaneous circulation; ROSC; cardiopulmonary resuscitation; CPR; cardiac arrest; methylene blue; MB; S-PBN; mild therapeutic hypothermia; MTH; targeted temperature management; TTM; endothelin; ET-1; ECE-1; ETAR; ETBR; nitric oxide; NO; nitric oxide synthase; NOS; eNOS; iNOS; nNOS; porcine; amiodarone; hypovolemia; milrinone; vasopressin; esmolol; epinephrine; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care; Medical Cell Biology; Medicinsk cellbiologi; Cardiology; Kardiologi;

   Sammanfattning : It is a major clinical problem that survival rates after out-of-hospital cardiac arrest have not markedly improved during the last decades, despite extensive research and the introduction of new interventions. However, recent studies have demonstrated promising treatments such as targeted temperature management (TTM) and methylene blue (MB). LÄS MER

3. 2. Cardiopulmonary Resuscitation : Pharmacological Interventions for Augmentation of Cerebral Blood Flow

   Författare :Jakob Johansson; Sten Rubertsson; Rolf Gedeborg; Sven-Erik Gisvold; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology and intensive care; Adrenaline epinephrine ; Cardiac arrest; Cardiopulmonary resuscitation; Cerebral blood flow; Guidelines; Post-resuscitation period; Vasopressin; Anestesiologi och intensivvård; Anaesthetics and intensive care; Anestesiologi och intensivvård;

   Sammanfattning : Cardiac arrest results in immediate interruption of blood flow. The primary goal of cardiopulmonary resuscitation (CPR) is to re-establish blood flow and hence oxygen delivery to the vital organs. LÄS MER

4. 3. Augmentation of vital organ blood flow during experimental cardiopulmonary resuscitation

   Författare :Rolf Gedeborg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Cardiac arrest; cardiopulmonary resuscitation; epinephrine; high-dose epinephrine; buffer; cerebral blood flow; post-resuscitation period; aortic occlusion; Kirurgi; Surgery; Kirurgi; Anestesiologi; Anaesthesiology;

   Sammanfattning : Clinical outcome from cardiac arrest remains poor. If the time from arrest to restoration of spontaneous circulation can be shortened and resuscitation techniques improved so that higher blood flow and oxygen delivery to vital organs is achieved, it is possible that the outcome from cardiac arrest could improve. LÄS MER

5. 4. Assessment of the Cerebral Ischemic/Reperfusion Injury after Cardiac Arrest

   Författare :Erik Mörtberg; Sten Rubertsson; Eldar Søreide; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intensive care; Intensivvård; Anaesthesiology and Intensive Care; Anestesiologi och intensivvård;

   Sammanfattning : The cerebral damage after cardiac arrest is thought to arise both from the ischemia during the cardiac arrest but also during reperfusion. It is the degree of cerebral damage which determines the outcome in patients. This thesis focuses on the cerebral damage after cardiac arrest. LÄS MER

7. 5. Experimental cardiopulmonary cerebral resuscitation : A study of cerebral perfusion with special reference to the postresuscitation disturbances

   Författare :Ala Nozari; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Cardiac arrest; cardiopulmonary resuscitation; cerebral blood flow; post-resuscitation period; epinephrine; vasopressin; aortic occlusion; isoprostane; Kirurgi; Surgery; Kirurgi; Anestesiologi; Anaesthesiology;

   Sammanfattning : Ischemic neuronal injury continues to be a major delimiting factor in achieving successful clinical outcomesafter resuscitation from cardiac arrest. In this thesis, a pig model of cardiopulmonary resuscitation (CPR) wasused to address the effects of different interventions on cerebral blood flow and oxygenation during CPR and theinitial postresuscitation period. LÄS MER