Sökning: "read together"

Visar resultat 1 - 5 av 110 avhandlingar innehållade orden read together.

  1. 1. Genomic adaptation and gene-dosage regulation of Drosophila melanogaster cells, and long-read software developments

    Författare :Jacob Lewerentz; Per Stenberg; Jan Larsson; Bergman Casey; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drosophila; cell line; long read; Nanopore; Pacbio; Illumina; cancer; genome evolution; dosage compensation; structural variant; software; bioinformatics;

    Sammanfattning : Cells are the vehicles that allows genetic code to proliferate in the world, taking on various forms – as illustrated by the tree of life. The cell features are determined by the manufacturing of proteins, a process that has its blueprints encoded as genes in the genome. LÄS MER

  2. 2. Genomic and evolutionary exploration of Asgard archaea

    Författare :Eva F. Caceres; Thijs J. G. Ettema; Simonetta Gribaldo; Uppsala universitet; []
    Nyckelord :archaea; Asgard; eukaryogenesis; metagenomics; genome binning; phylogenetics; phylogenomics; comparative genomics; gene tree-species tree reconciliation; ancestral reconstruction; long-read metagenomics;

    Sammanfattning : Current evolutionary theories postulate that eukaryotes emerged from the symbiosis of an archaeal host with, at least, one bacterial symbiont. However, our limited grasp of microbial diversity hampers insights into the features of the prokaryotic ancestors of eukaryotes. LÄS MER

  3. 3. Resolving the Genomic Complexity of Pediatric Acute Lymphoblastic Leukemia

    Författare :Yanara Marincevic-Zuniga; Ann-Christine Syvänen; Caroline Heckman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute lymphoblastic leukemia ALL ; 450k array; DNA methylation; RNA-sequencing; linked-read WGS; B-other; fusion gene; chromosomal translocation; Medicinsk genetik; Medical Genetics;

    Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer in the Nordic countries. Structural chromosomal rearrangements are a hallmark of ALL and represent key markers for diagnosis, risk stratification and prognosis. LÄS MER

  4. 4. Algorithms and statistical models for scaffolding contig assemblies and detecting structural variants using read pair data

    Författare :Kristoffer Sahlin; Lars Arvestad; Alexander Schönhuth; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Advances in throughput from Next Generation Sequencing (NGS) methods has provided new ways to study molecular biology. The increased amount of data enables genome wide scale studies of structural variation, transcription, translation and genome composition. LÄS MER

  5. 5. Internet use and digital participation in everyday life : Adolescents and young adults with intellectual disabilities

    Författare :Kristin Alfredsson Ågren; Helena Hemmingsson; Anette Kjellberg; Darren Chadwick; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Background: Internet use is an integral part of everyday life in contemporary society, especially among young people. It is used to perform activities in everyday life by an increasing proportion of the population. LÄS MER