Sökning: "proline metabolism"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden proline metabolism.

1. 1. The Role of Proline Catabolism in Candida albicans Pathogenesis

   Författare :Fitz Gerald S. Silao; Per O. Ljungdahl; Joachim Morschhäuser; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida albicans; proline metabolism; ATP; P5C; virulence; macrophage; hyphae; filamentation; Ras1 cAMP PKA; mitochondria; Proline dehydrogenase; P5C dehydrogenase; reactive oxygen species; Proline-P5C cycle; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : Candida albicans is an opportunistic fungal pathogen that has evolved in close association with human hosts. Pathogenicity is linked to an array of virulence characteristics expressed in response to environmental cues and that reflect the requirement to take up and metabolize nutrients available in the host. LÄS MER

3. 2. Biotic and abiotic stress in microorganisms and plants: Some Mechanisms of Stress and Programmed Cell Death. Genetic Engineering Approaches Towards Improved Stress Tolerance

   Författare :Per-Johan Meijer; Tillämpad biokemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biotic stress; plants; microorganisms; stress tolerance; antifreeze protein; proline; programmed cell death; systemic aquired resistance; Biochemistry; metabolism; Biokemi; Bioteknik; Biotechnology; abiotic stress;

   Sammanfattning : Various forms of stress, such as biotic and abiotic stress, were studied in microorganisms and plants to learn more about the underlying mechanisms of such stress and potential genetic engineering strategies towards stress tolerance. An antifreeze protein from winter flounder, expressed in E. LÄS MER

4. 3. Peptide-tagged proteins in aqueous two-phase systems

   Författare :Anna Nilsson; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biokemi; metabolism; Biochemistry; green fluorescent protein; cutinase; tryptophan; Aqueous two-phase system; peptide-tagged protein;

   Sammanfattning : This thesis deals with proteins containing peptide tags for improved partitioning in aqueous two-phase systems. Qualitatively the peptide-tagged protein partitioning could be predicted from peptide data, i.e. partitioning trends found for peptides were also found for the peptide-tagged proteins. LÄS MER

5. 4. Hydrophobic Fusion Tags: Implications For Bioseparation and Cellular Expression

   Författare :Anna Collén; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein production; secretion; aqueous two-phase systems; Trichoderma reesei; endoglucanase; Biochemistry; Metabolism; Biokemi; metabolism;

   Sammanfattning : The studies in this thesis have shown that the partitioning of endoglucanase I (EGI, Cel7B) from T. reesei could be significantly improved by relatively minor genetic engineering. By adding short peptides composed of tryptophan and proline residues to EGI, extreme partitioning could be obtained. LÄS MER

7. 5. Nitrogen and Redox Metabolism in Saccharomyces cerevisiae

   Författare :Eva Albers; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Saccharomyces cerevisiae; glutamate; protein expression; anaerobic physiology; nitrogen metabolism; redox; serine;

   Sammanfattning : Anaerobic conversion of glucose to ethanol by the yeast Saccharomyces cerevisiae has been studied. Glycerol is formed as a by-product in order to maintain the overall redox balance. LÄS MER