Sökning: "prediabetes"

Visar resultat 6 - 10 av 33 avhandlingar innehållade ordet prediabetes.

1. 6. Optimizing Exposome-wide Assessments in Cardiometabolic Risk

   Författare :Hugo Pomares-Millan; Genetisk och molekylär epidemiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lifestyle; Nutritional epidemiology; Cardiometabolic risk; Prediabetes; cardiovascular disease CVD ; Type 2 diabetes T2D ; Machine learning; causal inference; Mediation analysis; Mendelian randomization;

   Sammanfattning : This thesis is focused on cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D), two concomitant conditions that appear with growing concern. In our work, we aim to improve the identification of individuals at-risk of cardiometabolic disease through the characterization of complex environmental exposures (i.e. LÄS MER

3. 7. Metabolic and endocrine effects of SGLT2 inhibition

   Författare :Per Lundkvist; Jan Eriksson; Lars Lind; Maria J Pereira; Michael Alvarsson; Uppsala universitet; []
   Nyckelord :SGLT2 inhibition; GLP-1 receptor agonism; DPP4 inhibition; NAFLD; prediabetes; type 2 diabetes; obesity; metabolic syndrome; glucagon.; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Obesity and type 2 diabetes (T2D) are two growing global health problems with similar comorbidity profiles. SGLT2 inhibitors (SGLT2i) improve blood glucose control and can relieve both T2D and obesity, as well as their associated health problems such as hypertension, kidney failure, and cardiovascular disease. LÄS MER

4. 8. Lifestyle and glycaemic control before and after the onset of type 2 diabetes

   Författare :Robert Koivula; Genetisk och molekylär epidemiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Prediabetes; Obesity; Beta-cell Function; Insulin Sensitivity; Physical Activity; Exercise; Diet; Lifestyle; Ectopic Fat; Genetic Epidemiology; Genetic Risk; Biomarker; Precision Medicine;

   Sammanfattning : Type 2 diabetes (T2D) is a complex disease with widespread physiological insults to the regulation of metabolic homeostasis, above all glycaemic regulation. The pathogenesis of T2D and its progression is broadly understood to be through a gradual decrease in peripheral insulin sensitivity, a compensatory rise in insulin secretion, and a gradual decline in beta-cell function, resulting in glycaemic dysregulation and eventual T2D. LÄS MER

5. 9. Supporting healthy movement behaviours in people with metabolic risk, prediabetes, or type 2 diabetes in primary health care

   Författare :Kristina Larsson; Maria Hagströmer; Jenny Rossen; Unn-Britt Johansson; Åsa Norman; Stephanie Bonn; Sophiahemmet Högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The overall aim of this thesis was to investigate if a pedometer-based intervention inthe primary health care setting can support people with prediabetes or type 2 diabetestowards healthier movement behaviours. Moreover, health care professionals’experiences of supporting people with metabolic risk factors to increase theirphysical activity were explored. LÄS MER

7. 10. Support for physical activity in individuals with prediabetes and type 2 diabetes in primary care - the Sophia Step Study

   Författare :Jenny Rossen; Unn-Britt Johansson; Maria Hagströmer; Agneta Yngve; Mikael Fogelholm; Karolinska Institutet; Karolinska Institutet; Sophiahemmet Högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : A health promoting-care approach includes supporting the individual to increase control over and to improve his or her health to obtain the best possible wellbeing and quality of life. In prediabetes and type 2 diabetes regular physical activity is of pronounced importance for preventing complications and premature death as well as to enhance quality of life. LÄS MER