Sökning: "phosphomimetic substitution"

Hittade 2 avhandlingar innehållade orden phosphomimetic substitution.

  1. 1. Using peptide-phage display to capture conditional motif-based interactions

    Författare :Gustav Sundell; Ylva Ivarsson; Per Jemth; Attila Reményi; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein-protein interaction; PDZ domain; phosphorylation; peptide-phage display; ProP-PD; phospho-peptide; phosphomimetic substitution; Scribble; NMR; DLG1; PTM; affiinity; Biokemi; Biochemistry;

    Sammanfattning : This thesis explores the world of conditional protein-protein interactions using combinatorial peptide-phage display and proteomic peptide-phage display (ProP-PD). Large parts of proteins in the human proteome do not fold in to well-defined structures instead they are intrinsically disordered. LÄS MER

  3. 2. Functional interaction studies of different transmembrane proteins, activities occurring in the pore membrane and in the inner nuclear membrane

    Författare :Ellinor Crafoord; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Aim: The overall aim of my research has been to investigate protein‐protein interactions of nuclear envelope proteins. One specific aim has been to study the effect of mitotic phosphorylation on binding of the pore membrane protein gp210 to the nuclear pore complex. LÄS MER