Sökning: "oxindoles"
Hittade 3 avhandlingar innehållade ordet oxindoles.
1. New Methods for the Synthesis of Vicinal Stereocenters : Palladium-Catalyzed Domino Reactions and Asymmetric Transfer Hydrogenation
Sammanfattning : In this thesis the synthesis of vicinal stereocenters is investigated in two distinct contexts, namely the construction of 3,3-disubstituted oxindoles and the synthesis of b-hydroxy-a-amino acids. Both scaffolds are prevalent in a range of natural products and biologically relevant compounds and, therefore, methods for their synthesis are of great import. LÄS MER
2. Development of catalytic enantioselective C-C bond-forming and cascade transformations by merging homogeneous or heterogeneous transition metal catalysis with asymmetric aminocatalysis
Sammanfattning : Chiral molecules play a central role in our daily life and in nature, for instance the different enantiomers or diastereomers of a chiral molecule may show completely different biological activity. For this reason, it is a vital goal for synthetic chemists to design selective and efficient methodologies that allow the synthesis of the desired enantiomer. LÄS MER
3. Synthesis of indoles, bisindoles and indolocarbazoles : high affinity aryl hydrocarbon receptor ligands
Sammanfattning : This thesis deals with the synthesis and reactions of indoles, bisindoles, indolocarbazoles and their derivatives. New methods for ring formation of planar, heterocyclic quinones, with the indolo[3,2b]carbazole or indolo[2,3-b]carbazole structures are described. LÄS MER