Sökning: "narcolepsy"

Visar resultat 6 - 9 av 9 avhandlingar innehållade ordet narcolepsy.

  1. 6. Array-based Autoantibody Profiling and Epitope Mapping

    Författare :Arash Zandian; Peter Nilsson; Jochen M. Schwenk; Maja Neiman; Morten Nielsen; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; antibody; antigens; peptide; epitope mapping; autoimmunity; autoantibodies; microarrays; Bioteknologi; Biotechnology;

    Sammanfattning : Antibodies are a class of proteins that are made by the immune system to recognize harmful organisms and molecules. Their exceptional capability of specifically recognizing molecules has been investigated for over a century and information thereof has been utilized for a variety of applications including vaccine and generation of therapeutic antibodies. LÄS MER

  3. 7. Neurotransmitter Imaging of the Human Brain : Detecting γ-Aminobutyric Acid (GABA) Using Magnetic Resonance Spectroscopy

    Författare :Sofie Tapper; Peter Lundberg; Anders Tisell; Peter Zsigmond; Richard Edden; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Introduction: In this thesis, MEGA-edited Magnetic Resonance Spectroscopy (MRS) has been used for the purpose of non-invasive detection of !- aminobutyric acid (GABA) within the brain. GABA is the main inhibitory neurotransmitter in the human central nervous system, and glutamate is the corresponding main excitatory neurotransmitter. LÄS MER

  4. 8. Exploring Brain Gene Expression i Animal Models of Behaviour

    Författare :Julia Lindberg; Elena Jazin; Peter Saetre; Jonathan Flint; Uppsala universitet; []
    Nyckelord :Biology; behavioural genetics; gene expression; brain; microarray analysis; domestication; animal model; haem; Canis familiaris; Vulpes vulpes; Mus musculus; Biologi;

    Sammanfattning : The genetic basis for behavioural traits is largely unknown. The overall aim of this thesis was to find genes with importance for behavioural traits related to fear and anxiety. Microarray analysis was used to screen expression profiles of brain regions important for emotional behaviour in dogs, wolves, foxes and mice. LÄS MER

  5. 9. Neuroproteomic profiling of human body fluids

    Författare :Anna Häggmark; Peter Nilsson; Jochen M. Schwenk; Katrin Marcus; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bioteknologi; Biotechnology;

    Sammanfattning : This thesis provides results from affinity based studies where human body fluids were profiled to find markers for neurological diseases. Both proteins and autoantibodies were analysed using microarray technologies that can profile hundreds of analytes and hundreds of samples in parallel using small sample volumes. LÄS MER