Sökning: "mitogen-activated protein kinase kinase 3"

Visar resultat 1 - 5 av 52 avhandlingar innehållade orden mitogen-activated protein kinase kinase 3.

  1. 1. Cyclic Nucleotide Phosphodiesterase 3B: Regulation in rat adipocytes and 3T3-L1 cells

    Författare :Tova Landström; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3T3-L1 TNF-alpha; adipocyte; insulin; p70S6 kinase; mitogen-activated protein kinase; protein kinase B; phosphatidylinositol-3 kinase; phosphodiesterase 3B; cAMP; lipolysis; phosphorylation; signal transduction; Biochemistry; Metabolism; Biokemi; metabolism;

    Sammanfattning : Insulin stimulation of rat adipocytes results in phosphorylation and activation of the cyclic nucleotide phosphodiesterase 3B (PDE3B), a key enzyme in the antilipolytic signalling pathway of this hormone. In this thesis, the site phosphorylated in PDE3B upon stimulation of rat adipocytes with insulin and/or the beta-adrenergic agonist, isoproterenol is identified. LÄS MER

  3. 2. Organelle movement in melanophores: Effects of Panax ginseng, ginsenosides and quercetin

    Författare :Therese Eriksson; Rolf Andersson; Samuel Svensson; Ingemar Lundström; Robert Kronstrand; Per Hammarström; Linköpings universitet; []
    Nyckelord :melanophores; Panax ginseng; ginsenosides; quercetin; organell anterograde transport; endothelin-3; mitogen activated protein kinase; protein kinase C; MEDICINE; MEDICIN;

    Sammanfattning : Panax ginseng is a traditional herb that has been used for over 2000 years to promote health and longevity. Active components of ginseng include ginsenosides, polysaccharides, flavonoids, polyacetylenes, peptides, vitamins, phenols and enzymes, of which the ginsenosides are considered to be the major bioactive constituents. LÄS MER

  4. 3. Exercise effects on the mitogen-activated protein (MAP) kinase cascade in skeletal muscle

    Författare :Ulrika Widegren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :skeletal muscle; MAP kinase; contraction; acute exercise; Akt kinase; exercise intensity; signal transduction; fiber-type;

    Sammanfattning : Exercise-induced adaptations in skeletal muscle are regulated by numerous signaling mechanisms. However, little is known about the molecular signaling mechanisms linking muscle contraction or other exercise-associated stimuli to intracellular responses in skeletal muscle. LÄS MER

  5. 4. Adenosine receptor signaling and the activation of mitogen-activated protein kinases

    Författare :Gunnar Schulte; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The nucleoside adenosine is present in all cells and body fluids of all living organisms; its production, both intracellularly and extracellularly, is tightly coupled to energy consumption resulting in increasing extracellular adenosine levels with increased energy consumption. Adenosine is metabolized by adenosine deaminase and adenosine kinase. LÄS MER

  7. 5. Signalling to Activation of Cytosolic Phospholipase A2 and Arachidonate Release in Macrophages

    Författare :Gösta Hiller; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal transduction; dexamethasone; macrophages; phospholipase C; phosphatidylinositol 3-kinase; mitogen-activated protein kinases; cytosolic phospholipase A2; arachidonic acid; Histology; cytochemistry; histokemi; cytokemi; tissue culture; Histologi; vävnadskultur; histochemistry;

    Sammanfattning : Eicosanoids include prostaglandins, thromboxanes and leukotrienes, which are arachidonic acid oxygenation products. These lipids make important contributions to the signs and symptoms of inflammatory diseases. LÄS MER