Sökning: "aldosterone"

Visar resultat 1 - 5 av 62 avhandlingar innehållade ordet aldosterone.

  1. 1. Genetic Alterations and Molecular Signatures in Aldosterone Producing Adenomas

    Författare :Tobias Åkerström; Peyman Björklund; Tracy Ann Williams; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aldosterone; aldosterone producing adenoma; KCNJ5; ATP1A1; ATP2B3; CACNA1D; CTNNB1;

    Sammanfattning : Primary Aldosteronism (PA) is caused by autonomous overproduction of aldosterone. Aldosterone is necessary for fluid and ion homeostasis. Aberrant overproduction leads to hypertension and cardiovascular damage. LÄS MER

  3. 2. The kallikrein-kinin system in primary hypertension : dynamics of circulating components of the kallikrein-kinin system in relation to the renin-angiotensin-aldosterone system

    Författare :K. Peter Öhman; Linköpings universitet; []
    Nyckelord :aldosterone; angiotensin Il; blood pressure; human; prekallikrein; renin; tissue kallikrein; MEDICINE; MEDICIN;

    Sammanfattning : Kinins are potent vasodilatory and blood pressure lowering peptides, with additional effects on renal handling of electrolytes and water. The kallikrein-kinin system consists of two separate entities, one confined to the circulation and the other to both tissues and the circulation. LÄS MER

  4. 3. Primary Aldosteronism Screening and Diagnosis in Primary Health Care

    Författare :Christina Westerdahl; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hypertension; primary health care; aldosterone; primary aldosteronism; fludrocortisone; aldosterone to renin ratio; renin; captopril;

    Sammanfattning : Arterial hypertension is a very common disorder. In most cases the cause is unknown and therefore classified as essential or primary hypertension. Primary aldosteronism (PA), characterized by an inappropriate aldosterone secretion, has traditionally been estimated to account for approximately 1 % of all hypertensive cases. LÄS MER

  5. 4. Betydelsen av inflammation och reninangiotensin- aldosteron-systemet vid ångest och depression

    Författare :Ludvig Hallberg; Lund Psykiatri; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; depression; anxiety; suicide; renin; aldosterone; inflammation; exercise;

    Sammanfattning : A number of biological systems have been studied in the past in an attempt to find the underlying cause of anxiety and depression. The main aim of the work described in this thesis was to investigate the importance of inflammation and the renin-angiotensin-aldosterone system (RAAS) in relation to anxiety and depression. LÄS MER

  7. 5. Molecular studies of endocrine tumors : Insights from genetics and epigenetics

    Författare :Samuel Backman; Per Hellman; Peter Stålberg; Olov Norlén; Robert Bränström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroendocrine tumors; Carcinoid; Pheochromocytoma; Aldosterone; Cancer; MEN1; Multiple endocrine neoplasia; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Endocrine tumors may be benign or malignant and may occur in any of the hormone producing tissues. They share several biological characteristics, including a low mutation-burden, and may co-occur in several hereditary tumor syndromes. The aim of this thesis was to identify genetic and epigenetic aberrations in endocrine tumors. LÄS MER