Sökning: "hypercoagulability"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet hypercoagulability.

  1. 1. Development of a Method to Measure Plasma Levels of Activated Protein C in Complex with Protein C Inhibitor

    Författare :Karin Strandberg; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein C inhibitor; activated protein C; hypercoagulability; deep vein thrombosis; Clinical chemistry; myocardial infarction; Klinisk kemi;

    Sammanfattning : Acute myocardial infarction (MI) and deep venous thrombosis (DVT) are conditions caused by thrombus formation with activation of the coagulation system. The plasma concentration of the complex between activated protein C (APC) and protein C inhibitor (PCI), APC–PCI complex is increased in such states. LÄS MER

  3. 2. Factor V Leiden mutation and pregnancy. Haemostasis during pregnancy in non-carriers and carriers of factor V Leiden mutation, with special emphasis on placenta-mediated and venous thromboembolic complications and on blood coagulation and fibrinolysis markers for prediction of complications

    Författare :Ulla Kjellberg; Göteborgs universitet; []
    Nyckelord :Activated protein C; D-dimer; Factor V Leiden; fibrinolysis; haemostasis; obstetric complications; platelet function; pregnancy; prothrombin fragment 1 2; soluble fibrin; Sonoclot; thrombosis;

    Sammanfattning : Factor V Leiden (FVL) mutation elevates the risk of venous thromboembolism (VTE) in general. During pregnancy, the haemostatic balance is changed in the direction of hypercoagulability, resulting in an increased incidence of VTE. 42 women were followed longitudinally during pregnancy and the puerperium. LÄS MER

  4. 3. Clinical evaluation and implications of left atrial remodeling in atrial fibrillation : From silent cerebral lesions and atrial stunning to novel electrocardiographic tools for prediction of arrhythmia outcome

    Författare :Panagiotis Arvanitis; Carina Blomström-Lundqvist; Mårten Rosenqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrial fibrillation; left atrial remodeling; recurrence; new-onset; silent cerebral lesions; white matter hyperintensities; cardioversion; pulmonary vein isolation; risk factors; electrocardiographic predictors; P-wave indices; machine learning; predictive models; Covid-19;

    Sammanfattning : Atrial fibrillation (AF) is the most common cardiac arrhythmia. Left atrial (LA) remodeling and reverse remodeling are associated with cerebral involvement and cognitive function (CF) changes. Risk stratification for AF related outcomes is essential in the management of patients with AF. LÄS MER

  5. 4. Effects of lipid-lowering treatment on platelet function and hemostatic mechanisms in diabetic patients : influence of chronic kidney disease and inflammatory parameters

    Författare :Tora Almquist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diabetes mellitus (DM) and chronic kidney disease (CKD) are both associated with increased cardiovascular morbidity and mortality, and the risk is even higher when they are concurrent. Both diseases are considered to be prothrombotic states with increased inflammatory activity and major disturbances in the hemostasis. LÄS MER

  7. 5. Studies of haemostasis in acute coronary syndromes and diabetes mellitus

    Författare :Mika Skeppholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The pathophysiology of acute coronary syndromes (ACS) includes atherosclerotic plaque rupture and coronary thrombus formation. Antithrombotic treatment is effective but recurrent atherothrombotic or bleeding complications are not uncommon. LÄS MER