Sökning: "haemostasis"

Visar resultat 1 - 5 av 46 avhandlingar innehållade ordet haemostasis.

1. 1. Factor V Leiden mutation and pregnancy. Haemostasis during pregnancy in non-carriers and carriers of factor V Leiden mutation, with special emphasis on placenta-mediated and venous thromboembolic complications and on blood coagulation and fibrinolysis markers for prediction of complications

   Författare :Ulla Kjellberg; Göteborgs universitet; []
   Nyckelord :Activated protein C; D-dimer; Factor V Leiden; fibrinolysis; haemostasis; obstetric complications; platelet function; pregnancy; prothrombin fragment 1 2; soluble fibrin; Sonoclot; thrombosis;

   Sammanfattning : Factor V Leiden (FVL) mutation elevates the risk of venous thromboembolism (VTE) in general. During pregnancy, the haemostatic balance is changed in the direction of hypercoagulability, resulting in an increased incidence of VTE. 42 women were followed longitudinally during pregnancy and the puerperium. LÄS MER

3. 2. Imaging methods for haemostasis research

   Författare :Lars Faxälv; Tomas Lindahl; Pentti Tengvall; Rolf Larsson; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Blood is a vital part of the human physiology; a transport system that brings nutrients and oxygen to sustain living cells and simultaneously facilitates the removal of carbon dioxide and other waste products from the body. To assure the continuity of these functions, it is of uttermost importance to keep the flowing blood inside the vascular system at any cost. LÄS MER

4. 3. On inflammation and cardiovascular disease in patients with rheumatoid arthritis

   Författare :Solveig Wållberg Jonsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; mortality; cardiovascular disease; ischemic heart disease; inflammation; lipids; Lp a ; haemostasis; fibrinolysis; atherogenesis; thrombogenesis;

   Sammanfattning : Patients with rheumatoid arthritis (RA) have a shorter life span than the general population. An increased death due to cardiovascular disease (CVD) has been reported. RA is characterized by synovitis and joint destruction accompanied by an acute phase reaction and systemic features. LÄS MER

5. 4. Studies of platelet signalling and endothelial cell responses using unique synthetic drugs

   Författare :Caroline Kardeby; Magnus Grenegård; Knut Fälker; Liza Ljungberg; Alastair W. Poole; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haemostasis; glycopolymers; purine analogue; PEAR1; GPIbα; CLEC-2; inflammation; ROCK;

   Sammanfattning : Haemostasis is a complex and tightly regulated process which protects us from bleeding. Platelets are essential for maintained haemostasis. Under normal conditions platelets are calmed by antithrombotic substances release by the endothelium. During vascular injury, the platelets will activate and form a haemostatic plug to prevent bleeding. LÄS MER

7. 5. Heparin coating and cardiotomy suction in cardiopulmonary bypass

   Författare :Staffan Svenmarker; Torkel Åberg; Gunnar Engström; Thomas Karlsson; Jarle Vaage; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; cardiopulmonary bypass; oxygenators; heparin; S100 proteins; blood loss; haemostasis; memory; outcome and process assessment; Kirurgi; Surgery; Kirurgi; kirurgi; Surgery;

   Sammanfattning : The present thesis addresses various means of reducing inflammatory responses associated with cardiopulmonary bypass (CPB) and retransfusion of pericardial suction blood (PSB) during cardiac surgery. Four (I-IV) prospective randomised controlled clinical trials comprising 475 patients were performed in the following areas: effects of heparin coating on measures of clinical outcome and memory function (I, II), inflammatory reactions in PSB and its systemic effects after retransfusion using cardiotomy suction or cell salvage (III) and effects of retransfusion of PSB on memory function and release patterns of protein S100B (IV). LÄS MER